Switch of breast tumors to HER2-low might provide greater therapeutic options
ANI |
Updated: May 09, 2021 18:56 IST
Lugano [Switzerland], May 9 (ANI): The finding that breast tumours can evolve to express low HER2 potentially widens the number of patients who can benefit from new investigational agents, typically novel antibody-drug conjugate therapies, that are currently in clinical trials for HER2-low tumours.
The first study of its kind exploring how breast cancers change from the primary to the recurrent tumour has revealed that nearly 30% of breast cancer patients convert from, or to, human epidermal growth factor receptor (HER)2-low status. The study was published in the journal Annals of Oncology.