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Dynamic model of SARS-CoV-2 spike protein reveals potential new vaccine targets

 E-Mail IMAGE: In this visualization of antibody target sites, the SARS-CoV-2 spike protein is tethered to the viral membrane with a slender stalk. Patches of intense purple color at the surface of... view more  Credit: Mateusz Sikora, Sören von Bülow, Florian E. C. Blanc, Michael Gecht, Roberto Covino and Gerhard Hummer A new, detailed model of the surface of the SARS-CoV-2 spike protein reveals previously unknown vulnerabilities that could inform development of vaccines. Mateusz S...
Mateusz Sikora Entwicklung Wissenschaftlich Human Frontier Science Program Frankfurt Institute For Advanced Max Planck Institute Of Biophysics Leibniz Supercomputing Centre Munich

Evidence of Antarctic glacier's tipping point confirmed for first time

Credit: Dr Sebastian Rosier Researchers have confirmed for the first time that Pine Island Glacier in West Antarctica could cross tipping points, leading to a rapid and irreversible retreat which would have significant consequences for global sea level. Pine Island Glacier is a region of fast-flowing ice draining an area of West Antarctica approximately two thirds the size of the UK. The glacier is a particular cause for concern as it is losing more ice than any other glacier in Antarctica. Cur...
United States United Kingdom Hilmar Gudmundsson Amundsen Sea Environmental Sciences International Thwaites Glacier Collaboration

First-of-its-kind mechanical model simulates bending of mammalian whiskers

 E-Mail IMAGE: Mechanics is key to whisker tactile sensation. When a whisker is deflected, its deformation profile within the follicle determines the activity of different groups of mechanoreceptors. view more  Credit: Yifu Luo and Nadina Zweifel Researchers have developed a new mechanical model that simulates how whiskers bend within a follicle in response to an external force, paving the way toward better understanding of how whiskers contribute to mammals sense of touch. Yifu Luo a...
Yifu Luo Mitra Hartmann Northwestern University Biomechanics Biophysics Zoology Veterinary Science Mathematics Statistics

Keeping it fresh: New AI-based strategy can assess the freshness of beef samples

 E-Mail IMAGE: Consuming spoiled beef is dangerous, but there are currently no simple and efficient methods to assess beef freshness. view more  Credit: Unsplash Although beef is one of the most consumed foods around the world, eating it when its past its prime is not only unsavory, but also poses some serious health risks. Unfortunately, available methods to check for beef freshness have various disadvantages that keep them from being useful to the public. For example, chemical analy...
South Korea Kwangju Gwangyoksi Kyoobin Lee Jae Gwan Kim Gwangju Institute Of Science Gwangju Institute

Consumers are searching online but not buying. Why?

Key Takeaways: Discounting or couponing is not the most effective way to tap the power of retargeting in online marketing. Customized seller recommendations may be more powerful than discounting. Seller auctions that allow marketers to self-select in the retargeting process improve cost efficiency. CATONSVILLE, MD, April 1, 2021 - Online marketers have seen the pattern: 95%-98% of online visitors search for something, but the search never converts into a purchase and they leave the site without...
United States Thai Che Zhenling Jiang Youwei Wang University Of California Wharton School

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The city formula

 E-Mail (Vienna, March 17, 2021) When complex systems double in size, many of their parts do not. Characteristically, some aspects will grow by only about 80 percent, others by about 120 percent. The astonishing uniformity of these two growth rates is known as "scaling laws." Scaling laws are observed everywhere in the world, from biology to physical systems. They also apply to cities. Yet, while a multitude of examples show their presence, reasons for their emergence are still a matter of de...
Stefan Thurner Carlos Molinero Royal Society Interface Complexity Science Hub Vienna Earth Science Energy Sources

New study investigates how life on land recovered after

 E-Mail IMAGE: The plant-eating pareiasaurs were preyed on by sabre-toothed gorgonopsians. Both groups died out during the end-Permian mass extinction, or "The Great Dying. " view more  Credit: © Xiaochong Guo SAN FRANCISCO (March 16, 2021) - Over the course of Earths history, several mass extinction events have destroyed ecosystems, including one that famously wiped out the dinosaurs. But none were as devastating as "The Great Dying," which took place 252 million years ago during t...
United States Mike Benton Peter Roopnarine Yuangeng Huang Zhong Qiang Chen China University Of Geosciences

Identifying cells to better understand healthy and diseased behavior

 E-Mail IMAGE: Georgia Tech researchers use a graphical model framework to uncover a better way to identify cells and understand neural activities in the brain. view more  Credit: Christopher Moore, Georgia Tech In researching the causes and potential treatments for degenerative conditions such as Alzheimers or Parkinsons disease, neuroscientists frequently struggle to accurately identify cells needed to understand brain activity that gives rise to behavior changes such as declining m...
United States Georgia Institute Of Technology Yueyi Li Dhavals Patel Yun Zhang Shivesh Chaudhary

Global warming helps invasive species flourish - study models likely combined effects on ecosystems

 E-Mail Increased global temperatures help invasive species establish themselves in ecosystems, new research led by a Swansea University bioscientist has shown. The study, published by the Royal Society, gives an insight into the probable combined effects of species invasions, which are becoming more common, and global warming. Climate warming and biological invasions result in the loss of species. They also alter the structure of ecosystems and the ways in which species interact. While there ...
United Kingdom Kevin Sullivan Miguel Lurgi Research Excellence Framework Royal Society Centre National

Modelling speed-ups in nutrient-seeking bacteria

 E-Mail Many bacteria swim towards nutrients by rotating the helix-shaped flagella attached to their bodies. As they move, the cells can either run in a straight line, or tumble by varying the rotational directions of their flagella, causing their paths to randomly change course. Through a process named chemotaxis, bacteria can decrease their rate of tumbling at higher concentrations of nutrients, while maintaining their swimming speeds. In more hospitable environments like the gut, this helps...
United Kingdom Theresa Jakuszeit University Of Cambridge Ottavio Croze Nutrition Nutrients Mathematics Statistics

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