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Active & iterative data-dependent reinjection logic for maintaining throughput, uptime, and consistency in triple quadrupole LC/MS analysis

The 6475 triple quadrupole LC/MS system with MassHunter 12 features an intelligent workflow called iReflex, an intelligent automated worklist reinjection logic tool to maximise analytical throughput or ensuring samples are within tolerance.  In the application note, Agilent Technologies demonstrates three iReflex workflows, that can operate concurrently in one worklist to ensure samples are measured within SOP guidelines. 
Agilent Technologies Application Note Application Notes Scientific Posters Case Studies Application Articles

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An end-to-end software algorithm for LC/MS/MS method development, optimization, and QA/QC deployment

The new 6475 triple quadrupole LC/MS system with MassHunter 12 includes an intelligent MRM and source optimizer that is built into the method editor.  In this application note, Agilent Technologies demonstrates that this intelligent optimizer can be used to create a new method from scratch, add new components ton an existing method, and fine tune or verify parameters of an existing method. 
Agilent Technologies Application Note Application Notes Scientific Posters Case Studies Application Articles

Accelerated lifetime testing with real-time Early Maintenance Feedback (EMF) diagnostic monitoring on the 6475 triple quadrupole LC/MS

To help alleviate concerns on instrument health and longevity, the new Agilent 6475 triple quadrupole LC/MS system was designed with onboard intelligence that actively reports on the instrument health and status through Early Maintenance Feedback (EMF).  In this application note, Agilent Technologies presents a use case to trigger EMF events to simulate heavy instrument use through 10,000 sample injections of spiked bovine urine. 
Agilent Technologies Application Note Early Maintenance Feedback Application Notes Scientific Posters Case Studies

Single cell protein secretion assays using Nanovials and the Amnis ImageStream XMk II Imaging Flow Cytometer

In this application note, Luminex describes a novel method involving a uniform hydrogel particle platform, created by Partillion Bioscience, called nanovial. Imaging flow cytometry is then used to simultaneously measure the individual cellular characteristics and secretions released from each specific cell.
Partillion Bioscience Amnis Imagestream Xmk Application Note Amnis Imagestream Low Cytrometry

Use of self-interaction parameters derived from light scattering experiments for better developability assessment of biologic therapeutics

In this application note, NanoTemper Technologies demonstrates how the Prometheus Panta measures self-interaction of proteins and allows researchers to prioritize candidates and improve outcomes. 
Application Note Nanotemper Technologies Prometheus Panta Light Scattering Biologic Therapeutics

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