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Study finds asymptomatic SARS-CoV-2 infection induced comparable memory B cell responses to mild symptomatic infection in young adults

Researchers identified that among healthy young adults, the development of SARS-CoV-2 triggered memory B cell and antibody reactions were equivalent following mildly symptomatic or asymptomatic infections.
United States Kateryna Kon Shutterstock Health Action Response For Marines Infectious Diseases Action Response United States Marine Corps

A different approach to build a more durable, broadly effective COVID-19 vaccine

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new and emerging variants and could be taken as a pill, by inhalation or other delivery methods.
San Diego United States University Of California San Diego Aaronf Carlin Maurizio Zanetti Emily Henderson

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Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

A recent study posted to the bioRxiv* preprint server supports using mosaic sarbecovirus receptor-binding domain (RBD)-nanoparticles to discover therapeutic pan-variant and pan-sarbecovirus monoclonal antibodies (mAbs) and to induce mAbs by vaccination.
Spytagged Rbds California Institute Of Technology Beckman Research Institute Of City Hope Stanford University Beckman Research Institute California Institute

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