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Discovery provides critical clues to why many immunotherapies trigger dangerous side effects

It's not often that a failed clinical trial leads to a scientific breakthrough. When patients in the UK started showing adverse side effects during a cancer immunotherapy trial, researchers at La Jolla Institute for Immunology (LJI) Center for Cancer Immunotherapy and University of Liverpool went back through the data and worked with patient samples to see what went wrong.
United Kingdom Pandurangan Vijayanand Christianh Ottensmeier Simon Eschweiler Mitchell Kronenberg Emily Henderson

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Neutralization potency against the Omicron variant of naturally expressed MBC-derived IgG antibodies from vaccinated individuals

Researchers have shown how the Omicron variant of the SARS-CoV-2 successfully evaded a large fraction of antibodies derived from memory B cells, giving rise to a reduced, but incomplete immune escape.
Coronavirus Disease Covid 19 Covid 19 B Cell Ars Cov 2 Evere Acute Respiratory Evere Acute Respiratory Syndrome

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