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Study reveals mechanism of a previously unexplained type of cell death

A study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Cell Biology, details a previously unexplained type of cell death called disulfidptosis that could open the door for novel cancer therapeutic strategies.
United States Junjie Chen Emily Henderson Cancer Research Cancer Research Industry University Of Texas Md Anderson Cancer Center

Mitochondrial enzyme found to block cell death pathway points to new cancer treatment strategy

Date Time Mitochondrial enzyme found to block cell death pathway points to new cancer treatment strategy The mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) plays an important and previously unknown role in blocking a form of cell death called ferroptosis, according to a new study published today in Nature by researchers at The University of Texas MD Anderson Cancer Center. Preclinical findings suggest that targeting DHODH can restore ferroptosis-driven cell death, pointing to new the...
New York United States University Of Texas Li Zhuang Shiqi Wu Hyemin Lee

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