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The 2 Minute Medicine Podcast Episode 37 | 2 Minute Medicine

Welcome to the 2 Minute Medicine Podcast, summarizing the latest medical studies, curated and written by practicing physicians. On this podcast, twice a month, we cover the latest in healthcare news and research evidence. Our episode is live! Episode Description We begin with a discussion about our article of the week entitled โ€œElectronic nicotine delivery
United States New York United Kingdom Chadwick Boseman Leonardo Dicaprio Thomas Su

European Commission Expands Approval of Bristol Myers Squibb's Reblozyl® (luspatercept) to Include First-Line Treatment of Transfusion-Dependent Anemia in Adults with Lower-Risk Myelodysplastic Syndromes (LR-MDS) -April 02, 2024 at 08:09 pm EDT

Approval of Reblozyl is based on head-to-head, pivotal Phase 3 COMMANDS study, in which Reblozyl nearly doubled the percentage of patients achieving transfusion independence and hemoglobin increase,...
United Kingdom United States Bristol Myers Squibb Monica Shaw Leukemia Unit At Humanitas Cancer Center Acceleron Pharma Inc

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Baricitinib preserves beta cell function in new-onset type 1 diabetes

1. In this randomized controlled trial, baricitinib, a Janus kinase (JAK) inhibitor, preserved beta cell function and reduced insulin requirement compared to placebo in patients with new-onset type 1 diabetes mellitus (T1DM). 2. Patients receiving baricitinib also demonstrated tighter glycemic control compared to those receiving the placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: The
Minute Medicine Inc Rating Level Confidence Interval

Tenecteplase is equivalent to placebo between 4.5 and 24 hours after stroke onset

1. In this randomized controlled trial, tenecteplase administered at 4.5 to 24 hours after stroke onset to patients with an occluded middle cerebral artery (MCA) or internal carotid artery (ICA) was not superior to placebo. 2. Tenecteplase did not differ from placebo with regards to rates of death and symptomatic intracranial hemorrhage. Evidence Rating Level:
Minute Medicine Inc Rating Level Confidence Interval

Seladelpar improves symptoms of primary biliary cholangitis

1. In this randomized controlled trial, among patients with primary biliary cholangitis (PBC) who had had inadequate response to ursodeoxycholic acid, seladelpar was superior to placebo in achieving biochemical response and symptomatic management. 2. Seladelpar had an acceptable safety profile, with similar rates of adverse events to a placebo. Evidence Rating Level: 1 (Excellent) Study
Minute Medicine Inc Rating Level Confidence Interval Chronic Disease Primary Biliary Cholangitis Ursodeoxycholic Acid

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