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CHMP Adopts Positive Opinion Recommending Approval of Bristol Myers Squibb's Opdivo® (nivolumab) in Combination with Cisplatin and Gemcitabine for the First-Line Treatment of Adult Patients with Unresectable or Metastatic Urothelial Carcinoma

Recommendation based on results from CheckMate -901, the first Phase 3 trial with an immunotherapy-chemotherapy combination to demonstrate a survival benefit versus standard-of-care chemotherapy...
United States South Korea Bristol Myers Squibb Dana Walker European Medicines Agency Company Opdivo

Microaxial flow pump improves infarct-related cardiogenic shock outcomes

1. In this randomized controlled trial, in patients with infarct-relate cardiogenic shock, death from any cause was lower in the group that received the microaxial flow pump compared to the group that received the standard care. 2. The composite safety endpoint occurred in more patients in the microaxial flow pump group than in the standard
Minute Medicine Inc Rating Level Confidence Interval Cardiogenic Shock Infarct Related Cardiogenic Shock Microaxial Flow Pump

Beta-blockers do not lower mortality after myocardial infarction with preserved ejection fraction

1. In this randomized controlled trial, long-term beta-blockers did not impact all-cause mortality among patients with preserved left ventricular ejection fraction (LVEF) following an acute myocardial infarction (MI) and early angiography. 2. Long-term beta-blocker therapy was not associated with a higher risk of adverse events compared to no beta-blocker. Evidence Rating Level: 1 (Excellent) Study
Minute Medicine Inc Rating Level Confidence Interval Beta Blocker Chronic Disease Myocardial Infarction

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