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Novel assay may improve detection and treatment of acute myeloid leukemia

A novel assay that detects a unique molecular marker in patients with acute myeloid leukemia (AML) may revolutionize the way this disease is detected and treated according to a new report in The Journal of Molecular Diagnostics published by Elsevier.
Washington University School Of Medicine Department Of Medicine Division Of Oncology Molecular Diagnostics Washington University School Acute Myeloid Leukemia

"Measuring DNA quality by digital PCR using probability calculations" by David Gleerup, Yao Chen et al.

Background: Accurate methods to assess DNA integrity are needed for many biomolecular methods. A multiplex digital PCR (dPCR) method designed for interspaced target sequences can be used to assess sequence integrity of large DNA strands. The ratio of single positive partitions versus double positive partitions is then used to calculate the sheared DNA strands. However, this simple calculation is only valid with low DNA concentration. We here describe a method based on probability calculations wh...
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Source: uow.edu.au

Liquid biopsies can accurately detect residual disease in patients with cervical cancer, study confirms

Two liquid biopsy tests that look for the presence of human papillomavirus (HPV) in the blood accurately identified patients with a high risk of cervical cancer recurrence after the completion of chemoradiation, a new study confirms.
United States Megan Craig Kathy Han American Society For Radiation Oncology University Of Toronto Princess Margaret Cancer Center

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