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Study shows SARS-CoV-2 prompts NLRP3 inflammasome activation through spike-ACE2 receptor interaction

New research assesses the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation in response to SARS-CoV-2 and its spike protein, and the effects of this exposure in the presence of a-synuclein protein aggregate fibrils.
Mattlphotography Shutterstock Image Credit Coronavirus Disease Covid 19 Ars Cov 2 Central Nervous System Covid 19

Exploring the structural basis of antibody evasion and enhanced transmission of the SARS-CoV-2 Omicron variant

In a new study, researchers used cryogenic electron microscopy (cryo-EM) analysis to capture the open and closed states of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variantโ€™s spike protein.
Image Credit Graphpad Prism Coronavirus Disease Covid 19 Ars Cov 2 Ngiotensin Converting Enzyme 2 Electron Microscopy

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Cannabinoids may prevent infection with SARS-CoV-2, including variants

A new study published in the Journal of Natural Products of the American Chemical Society and American Society of Pharmacognosy has shown that isolated cannabinoids or those in hemp extracts have the potential to prevent and treat the infection with the severe acute respiratory syndrome coronavirus 2 (SARSโ€‘CoVโ€‘2) โ€“ primarily by blocking viral cell entry.
United States Dmytro Tyshchenko Shutterstock Linus Pauling Institute At Oregon State University American Society Of Pharmacognosy Natural Products American Chemical Society

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