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SARS-CoV-2 spike engagement of ACE2 shown to prime S2′ site cleavage and fusion initiation

In a new study, researchers used a cell-cell fusion assay to extract potentially cleaved spike protein products from syncytia in order to explore the functional and biochemical characteristics of spike (S) protein when it engages its receptor ACE2 in living cells.
University Of Chinese Academy Sciences Image Credit Chinese Academy Coronavirus Disease Covid 19 Ars Cov 2 Ngiotensin Converting Enzyme 2

4Bio Capital: 4BIO Capital Portfolio Company Carisma to Collaborate with Moderna to Develop in vivo Engineered Chimeric Antigen Receptor Monocytes (CAR-M) for Oncology

Press Release 4BIO Capital Portfolio Company Carisma to Collaborate with Moderna to Develop in vivo Engineered Chimeric Antigen Receptor Monocytes (CAR-M) for Oncology Collaboration
United States University Of Pennsylvania Allison Connolly Amber Fennell Steven Kelly Genevieve Wilson

New grant program launches to advance therapeutic discovery for follicular lymphoma

Today saw the launch of a dedicated grant program aimed at advancing therapeutic discovery for follicular lymphoma (FL), The Follicular Lymphoma Foundation (FLF) CURE FL Awards - Curative Research to Eliminate Follicular Lymphoma.
Mitchell Smith Nicola Mendelsohn Melissa Stevens Emily Henderson Curative Research To Eliminate Follicular Lymphoma Follicular Lymphoma Foundation

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