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Researchers identify how a critical schistosomiasis drug works on the molecular level

Independent teams from Texas Biomedical Research Institute and the Medical College of Wisconsin have published two papers in Science Translational Medicine identifying how the only approved drug to treat schistosomiasis, a widespread parasitic worm infection, works on the molecular level.
United States Medical College Of Wisconsin Jonathan Marchant Winka Le Clech Tim Anderson Le Clech

Novel insight into the immune characteristics of bats

Many studies have indicated that bats are significant reservoirs of innumerable viruses, such as influenza, coronaviruses, and rabies. These studies have also reported that bats predominantly remain asymptomatic or develop mild diseases during viral infections caused by henipaviruses, Ebola virus, coronaviruses, etc.
Coronavirus Disease Covid 19 Covid 19 Ene Expression Immune Response Ars Cov 2 Evere Acute Respiratory

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Scientists provide a structural framework for Omicron immune evasion and ACE2 receptor recognition

An interesting preprint research paper describes structural changes resulting from the multiple mutations found in the recent Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is the causative agent behind the coronavirus disease 2019 (COVID-19) pandemic. In addition, the research describes the consequent effects of these changes on Omicronโ€™s infectivity and immune evasion capabilities.
United States Delta Vocs Beta Vocs Coronavirus Disease Covid 19 Ngiotensin Converting Enzyme 2 Binding Affinity

Nucleocapsid protein preferentially binds to structured and longer RNA to deliver viral proteins in host circulation

Results from a new study could be crucial in studying the molecular and biochemical basis of SARS-CoV-2 infection at a more granular level and help in strategizing therapeutic solutions to treat and manage COVID-19 effectively.
Nhemz Shutterstock Image Credit Coronavirus Disease Covid 19 Ars Cov 2 Evere Acute Respiratory Evere Acute Respiratory Syndrome

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