1. In this prospective cohort study, hypertonic saline-stimulated copeptin was more accurate in diagnosing arginine vasopressin (AVP) deficiency than arginine-stimulated copeptin. 2. The diagnoses made by these tests were compared against final diagnoses by two independent endocrinologists. Evidence Rating Level: 1 (Excellent) Study Rundown: AVP deficiency, formerly known as central diabetes insipidus, is difficult to
A major clinical trial led by Queen Mary University of London and the Harvard T.H. Chan School of Public Health has found that vitamin D supplements do not increase bone strength or prevent bone fractures in children with vitamin D deficiency.
1. Mean HbA1c reduction at 26 weeks was comparable in the weekly icodec and daily degludec groups. 2. The risk of hypoglycemia was significantly higher among patients taking weekly insulin icodec compared to those taking daily insulin degludec. Evidence Rating Level: 1 (Excellent) Study Rundown: First-line therapy for type 1 diabetes includes a combination of
A common concern about gender-affirming hormone therapy for transmasculine people is the risk of red blood cell volume changes and erythrocytosis, a high concentration of red blood cells, with the use of prescribed testosterone.