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Study finds significant variation in biomarker test utilization and treatment for non–small-cell lung cancer

Study finds significant variation in biomarker test utilization and treatment for non–small-cell lung cancer Biomarker testing surveys specific disease-associated molecules to predict treatment response and disease progression; however its use has complicated the diagnosis of non-small-cell lung cancer (NSCLC). In a new study in The Journal of Molecular Diagnosis, published by Elsevier, investigators provide for the first time a complete overview of biomarker testing, spanning multiple treat...
Maarten Ijzerman Emily Henderson University Of Twente Services Research Health Technology University Of Melbourne Centre For Cancer Research

The unveiling of a novel mechanism of resistance to immunotherapy targeting HER2

 E-Mail IMAGE: Joaquín Arribas, co-Program Director of Preclinical and Translational Research at VHIO, ICREA Professor, CIBERONC Investigator, Director of the Hospital del Mar Medical Research Institute (IMIM). view more  Credit: VHIO Redirection of lymphocytes, via T-cell bispecific antibodies (TCBs) and chimeric antigen receptors (CARs), is already approved to treat some hematologic malignancies. In solid tumors these immune-based strategies continue to fail. Research led by J...
Comunidad Autonoma De Cataluna Comunidad Autonoma De Aragon Rius Ruiz Alex Mart Breast Cancer Research Foundation Health Institute Instituto De Salud Carlos

Study provides insight into the genetic landscape of polycystic kidney disease in Ireland

Study provides insight into the genetic landscape of polycystic kidney disease in Ireland A study has described genetic changes in patients with the most common form of hereditary kidney disease that affects an estimated 12.5 million people worldwide. The research, which focussed on Polycystic Kidney Disease (PKD) in Ireland, provides insights into PKD that will assist doctors and patients in the management of this of inherited condition. The study, led by researchers from the RCSI University o...
Gianpiero Cavalleri Peter Conlon Katherine Benson Emily Henderson University Of Medicine School Of Pharmacy

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Race may play an important role in children's food allergies

Race may play an important role in childrens food allergies Black children have significantly higher rates of shellfish and fish allergies than White children, in addition to having higher odds of wheat allergy, suggesting that , researchers at Ann & Robert H. Lurie Childrens Hospital of Chicago, Rush University Medical Center and two other hospitals have found. Results of the study were published in the February issue of the Journal of Allergy and Clinical Immunology: In Practice. Food allerg...
United States Rush University Medical Center Susan Fox Ruchi Gupta Mahboobeh Mahdavinia Ann Roberth Lurie

Study finds high bleeding risk in a sub-group of COVID-19 patients

Study finds high bleeding risk in a sub-group of COVID-19 patients The human body strives to keep itself in homeostasis, or balance. When blood clots are created, the bodys innate response is to break the clots down to prevent significant health problems from arising. Research has found that patients with COVID-19 are prone to serious blood clotting. This is why many patients receive high dose anticoagulants as part of their treatment. But a new study in Scientific Reports, led by senior autho...
United States Yu Ray Zuo Daniel Lawrence Emily Henderson Scientific Reports Basic Research

Food intake patterns are partly under genetic control, study shows

Food intake patterns are partly under genetic control, study shows Your food intake patterns are partly under genetic control, according to the latest research from researchers at Kings College London, published today in the journal Twin Research and Human Genetics. Researchers can study the quality of an individuals typical diet by using a type of analysis called dietary indices. Researchers use dietary indices to understand what foods someone eats and the nutrients provided, compared with re...
City Of United Kingdom Olatz Mompe Massimo Mangino Emily Henderson King College London

Study explores how choice of foods influences aging and lifespan in fruit flies

Study explores how choice of foods influences aging and lifespan in fruit flies Having a choice of foods may accelerate aging and shorten the lifespan of fruit flies, according to a study published today in the open-access eLife journal. While early experiments have shown that calorie restriction can extend lifespan, the current study adds to the growing body of evidence that suggests other diet characteristics besides calories may also influence aging and lead to earlier death. It has been re...
Ann Arbor United States Yang Lyu Scott Pletcher Williamh Howell Emily Henderson

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