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Full-genome CRISPR screen reveals surprising ways neurons survive oxidative stress

 E-Mail IMAGE: Super-resolution microscopy of a neuron shows the accumulation of lipids within lysosomes that occurs when the gene for prosaposin is suppressed. view more  Credit: UCSF When a single gene in a cell is turned on or off, its resulting presence or absence can affect the function and survival of the cell. In a new study appearing May 24 in Nature Neuroscience, UCSF researchers have successfully catalogued this effect in the human neuron by separately toggling each of the ...
United States San Francisco Kun Leng Martin Kampmann Anthony Abarientos Jonathan Weissman

Singleton To Direct New Intramural Effort for Dementia Research

Dr. Andrew Singleton Dr. Andrew B. Singleton is the director of a new NIH intramural research effort, the Center for Alzheimer’s and Related Dementias (CARD). He has been serving as CARD acting director since its construction plan launch in January 2020. He is set to stimulate and lead collaborative research group projects to expand knowledge of the biological mechanisms of Alzheimer’s and related dementias, and to explore methods of treatment and prevention.  “With his decades of experi...
United States United Kingdom Newcastle Upon Tyne Roberta Pritzker Andrewb Singleton Andrew Singleton
Source: nih.gov

NIMH » Branch Chief and Staff

Francesca Belouad, MA, is a Research Psychologist in GEB-SDGE. She is responsible for administrating interviews and overseeing clinical aspects of the NIMH Family Study. Francesca has been employed as a Research Psychologist at the NIMH since 2000, when she was recruited by Dennis Charney, MD, during the formation of the Mood and Anxiety Disorders Research Program. Prior to this, she held research positions at the Section on Development Psychology at the NIMH, Outpatient Psychiatry at the Wash...
United States College Park University Of Washington American University District Of Columbia West Bengal
Source: nih.gov

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NIMH » Rapidly-Acting Treatments for Treatment-Resistant Depression (RAPID)

Rapidly-Acting Treatments for Treatment-Resistant Depression (RAPID) Rapidly-Acting Treatments for Treatment-Resistant Depression (RAPID) is an NIMH-funded research project that promotes development of speedier therapies for severe, treatment-resistant depression. The initiative is supporting a team of researchers, led by Maurizio Fava, M.D., of Massachusetts General Hospital, who are identifying and testing promising pharmacological and/or non-pharmacological treatments that lift depression wi...
United States Intramural Research Program Rapidly Acting Treatments Treatment Resistant Depression Acting Treatments Massachusetts General Hospital
Source: nih.gov

NIMH » Section on Molecular Neuroscience Staff

Section on Molecular Neuroscience Staff Lee E. Eiden is the Chief of the Section on Molecular Neuroscience in the National Institute of Mental Health Intramural Research Program of the National Institutes of Health, Bethesda, Maryland. He received his B.A. in Chemistry from Northwestern University in Evanston Illinois, and Ph.D. in Pharmacology from The University of Kansas, and was a Staff Fellow, PRAT Fellow, and Senior Staff Fellow in the NIMH Intramural Research Program before joining the f...
New York United States Johns Hopkins University National Institutes Of Health Baylor College Of Medicine Abraham Worcel
Source: nih.gov

NIMH » Dr. Melissa Brotman Biography

Dr. Melissa Brotman Biography Dr. Melissa A. Brotman leads the Neuroscience and Novel Therapeutics Unit (NNT) in the Emotion and Development Branch at the National Institute of Mental Health (NIMH) Intramural Research Program (IRP). Dr. Brotman received her PhD in clinical psychology from the University of Pennsylvania, where she specialized in cognitive behavioral therapy for mood and anxiety disorders. After completing her clinical internship at the Veterans Affairs Maryland Health Care Syste...
United States Rockville Pike Melissaa Brotman Melissa Brotman Seymours Kety Career Development Institute Award
Source: nih.gov

NIMH » Mood Brain and Development Unit

Who We Are Stop/Play Principal Investigator Argyris Stringaris, MD, PhD, FRCPsych is a Senior Investigator at NIMH who researches and treats depression and related conditions in young people. He is also Professor of Clinical Psychiatry at Georgetown University. He trained in Child & Adolescent Psychiatry at the Maudsley Hospital in London and received his PhD from the Institute of Psychiatry, King’s College London. He served as an Attending Physician (Consultant Psychiatrist) at the National ...
New York United States Creighton University United Kingdom Columbia University Baylor College Of Medicine
Source: nih.gov

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