Major Bleeding News Today

Co-prescription of enzyme-inducing antiseizure medications is not associated with alteration in direct-acting oral anticoagulant efficacy or safety.

1. Annualized bleeding rate was reduced by 91% in the fitusiran prophylaxis group compared to the bypassing agents on-demand group. 2. 5% of patients in the fitusiran group reported thromboembolic events; there were no deaths. Evidence Rating Level: 1 (Excellent) Study Rundown: Hemophilia is marked by a deficiency in certain coagulation factors that make patients