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CHARLOTTE, N.C. — A history of COVID-19 nearly doubled the odds of having very short sleep, according to results from a large U.S. study presented at SLEEP 2022. “Few studies have focused on factors associated with sleep quantity and quality,” Marie-Rachelle Narcisse, PhD, lead study author and assistant professor at the University of Arkansas for Medical Sciences Northwest,

CHICAGO — In what researchers described as the first randomized controlled trial of chemotherapy in relapsed or refractory Ewing sarcoma, high-dose ifosfamide proved more effective in extending survival than topotecan and cyclophosphamide. Martin G. McCabe, MD, PhD, clinical senior lecturer in pediatric and adolescent oncology at University of Manchester in the U.K., presented the

CHICAGO — A combination of two targeted therapies significantly improved outcomes compared with standard care for children with BRAF V600 mutation-positive low-grade glioma, according to study results presented at ASCO Annual Meeting.Dabrafenib (Tafinlar, Novartis) and trametinib (Mekinist, Novartis) increased response rate, extended PFS and improved clinical benefit rate compared with

NEW ORLEANS — Risks for depression and suicidal ideation are higher among people with vs. without diabetes, and cases of suicide are likely underreported, according to a presenter at the American Diabetes Association Scientific Sessions. Katharine Barnard-Kelly, PhD, chief science officer at Spotlight Consultations in Portsmouth, U.K., professor at the Southern Health NHS Foundation

NEW ORLEANS — There is no single answer when it comes to determining the primary target for treating type 2 diabetes, two speakers said during a debate at the American Diabetes Association Scientific Sessions. Promoting weight loss to improve health outcomes for people with type 2 diabetes is one of the targets emphasized in the 2022 ADA Standard of Care. Ildiko Lingvay, MD, MPH, MSCS,

Abbott Nutrition restarted production of infant formulas at a Michigan plant that was shut down for months after the company initiated a recall of its powder formulas, beginning the country’s ongoing formula shortage.

NEW ORLEANS — New data show sustained glycemic improvements and safety at 1 year in very young children with type 1 diabetes who used a tubeless hybrid closed-loop insulin delivery system, researchers reported.Improved glycemic outcomes and safety in the initial 3-month pivotal study of the Omnipod 5 system (Insulet) in very young children persisted for an additional 9 months in an ongoing

People with food allergies showed lower risk for SARS-CoV-2 infection, whereas those with obesity had a higher risk, according to a study published in The Journal of Allergy and Clinical Immunology. Additionally, results of the perspective surveillance study showed asthma did not positively or negatively impact risk for SARS-CoV-2 infection.

The use of infliximab in patients with a deceased donor kidney transplant led to increased infections and did not improve allograft survival, according to data presented at the American Transplant Congress. “The intervention had no effect on allograft function or acute rejection,” Peter S. Heeger, MD, a professor of medicine and immunology at the Icahn School of Medicine at Mount

CHICAGO — Dostarlimab, an anti-PD-1 monoclonal antibody, demonstrated a 100% clinical complete response rate among a small cohort of patients with mismatch repair-deficient locally advanced rectal cancer, phase 2 study results showed.Longer follow-up is needed to examine the duration of treatment response in this patient population, according to researchers of the study, reported at ASCO