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Selexipag improves outcomes in PAH-associated connective tissue disease in real-world study

SAN FRANCISCO — New real-world data demonstrate treatment with selexipag improved outcomes in patients with pulmonary arterial hypertension associated with connective tissue disease.At the American Thoracic Society International Conference, Sean Gaine, MD, with the National Pulmonary Hypertension Unit at Mater Misericordiae Hospital in Dublin, Ireland, and colleagues reported patient
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Source: healio.com

Disparities in filled opioid use disorder prescriptions linked to COVID-19 pandemic

The COVID-19 pandemic was a likely cause for worsened disparities in buprenorphine and naltrexone access for opioid use disorder among minority groups compared with white patients, per a study published in JAMA Network Open. “Despite some progress in [medications for opioid use disorder] use, pre-pandemic evidence suggested that it was associated with frequent exposure to high out-of-pocket
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Source: healio.com

Aerobic exercise, pomegranate juice may reduce risk for type 2 diabetes

Aerobic training and daily intake of pure pomegranate juice may prevent increased liver enzymes and insulin resistance in adult men, according to findings from an Iranian study published in BMC Nutrition.“As pomegranate juice contains many polyphenolic and flavonoid compounds, it has strong antioxidant properties and prevents oxidative stress in the body,” Sasan Nemati, of the
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Source: healio.com

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Apellis submits NDA for pegcetacoplan for treatment of geographic atrophy

Apellis Pharmaceuticals submitted a new drug application to the FDA for intravitreal pegcetacoplan, a targeted C3 therapy for the treatment of geographic atrophy secondary to age-related macular degeneration, according to a press release.The submission is based on the results of the phase 3 DERBY and OAKS studies, as well as the phase 2 FILLY study. Pegcetacoplan demonstrated reduction in
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Source: healio.com

Stem cell therapy appears safe in advanced AMD, but questions remain

Stem cell therapy still has many hurdles to clear before becoming a viable therapeutic option for age-related macular degeneration, but it may have the potential to transform treatment in the future.“Overall, we have a huge problem with a major unmet need,” Rajesh C. Rao, MD, Leonard G. Miller Professor of Ophthalmology and Visual Sciences and associate professor in the departments of
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Source: healio.com

EULAR president: Education, advocacy critical for rheumatology's future

Elevating the rheumatology’s profile to policymakers, medical students and patients through advocacy and education is critical for the specialty’s future, according to EULAR President Annamaria Iagnocco, MD.“EULAR is 75 years old but looks much younger,” Iagnocco said in her opening remarks of the EULAR 2022 Congress. “The past is what we know and serves as a
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Source: healio.com

Transcatheter mitral valve repair safe, effective for patients with COPD

The presence of chronic obstructive pulmonary disease is not associated with intra-hospital or 1-year outcomes for patients with mitral regurgitation undergoing transcatheter mitral valve repair, data from a single-center study show.“Due to the concomitant risk factors, a relevant percentage of patients with CVD needing cardiac surgery or intervention have chronic obstructive pulmonary
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Source: healio.com

Vedolizumab, ustekinumab best anti-TNF for infection risk in older adult IBD

SAN DIEGO — Vedolizumab and ustekinumab associated with a lower risk for infection-related hospitalizations compared with anti-tumor necrosis factor agents in patients who initiated inflammatory bowel disease therapy at an older age. “It used to be thought that IBD becomes a milder disease with age and, therefore, there never was a tremendous investment in better understanding modern
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Source: healio.com

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