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CAR-T safe, effective for large B-cell lymphoma regardless of race or ethnicity

CHICAGO — Axicabtagene ciloleucel exhibited comparable efficacy and safety for large B-cell lymphoma regardless of patients’ race or ethnicity, according to study results presented at ASCO Annual Meeting.Data from a real-world analysis revealed some disparities in objective and complete response rates but no statistically significant differences in measures of treatment durability for
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Source: healio.com

Radiotherapy comparable to concurrent chemoradiotherapy in nasopharyngeal cancer subset

CHICAGO — Intensity-modulated radiotherapy conferred disease control and survival outcomes comparable to concurrent chemoradiotherapy but with less toxicity among patients with low-risk nasopharyngeal carcinoma, according to study results.The findings of the randomized phase 3 noninferiority trial, presented at ASCO Annual Meeting, suggested concurrent chemotherapy (CCRT) could be safely
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Source: healio.com

Q&A: Pegloticase sustained lower serum urate in kidney transplant recipients with gout

Among kidney transplant recipients with uncontrolled gout, pegloticase showed sustained decreased serum urate levels, according to findings presented at the American Transplant Congress.Patients also showed pain relief and decreased disability without worsening kidney function.
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Source: healio.com

Dupilumab improves sleep, function in people with chronic rhinosinusitis with nasal polyps

Patients with chronic rhinosinusitis with nasal polyps experienced improved sleep and functioning after 52 weeks of treatment with dupilumab, according to research published in The Journal of Allergy and Clinical Immunology: In Practice. These improvements in turn improved health-related quality of life, William Busse, MD, honorary associate and fellow in the department of medicine, division of
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Source: healio.com

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Non-urban stroke patients in New Zealand face poorer outcomes, lack critical care

Patients treated for stroke at non-urban hospitals in New Zealand experience poorer outcomes and face reduced access to crucial stroke interventions across the entire care spectrum, according to a study published in Neurology. “Departures from best practice stroke care in smaller, non-urban New Zealand hospitals have been accepted where a small population is dispersed over a wide geographic
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Source: healio.com

Lipid-lowering therapies underused for primary CVD prevention

In a cohort of more than 400,000 patients at high risk for CVD requiring primary prevention, less than half were taking appropriately dosed statins and less than 10% were taking nonstatin lipid-lowering therapies, researchers reported. For an abstract presented at the National Lipid Association Scientific Sessions, Ahmed A. Kolkailah, MD, cardiovascular medicine fellow at the University of Texas
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Source: healio.com

AREDS2 formula more effective at slowing AMD at 10 years

A dietary supplement that includes the antioxidants lutein and zeaxanthin helped slow progression of age-related macular degeneration.According to 10-year results from AREDS2, conducted by the National Institutes of Health, a new formula that replaced beta-carotene from the original AREDS formula with lutein and zeaxanthin reduced the risk for AMD progression in addition to being safer because of
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Source: healio.com

Virtual physical therapy may improve function, patient satisfaction after TKA

CHICAGO — Results showed patients who utilized a virtual physical therapy program after total knee arthroplasty had similar outcomes, but significant cost and time savings, compared with patients who used a formal physical therapy program.“Virtual physical therapy may not be the best option for some, but I think for the vast majority of patients that are getting hip and knee
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Source: healio.com

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