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Using next-gen CRISPR tool, Gladstone scienti

<p>In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing. Their findings, published in <em>Nature</em>, uncover detailed information that could help overcome the limitations of today’s immunotherapies and identify new drug targets for a wide range of disease...
San Francisco United States Mission Bay Justin Eyquem Carl Ward Vincent Allain

EQS-News: Pyrum Innovations AG: Chairman of the Supervisory Board increases his shareholding in the company Seite 1

27.02.2023 - EQS-News: Pyrum Innovations AG / Key word(s): Miscellaneous Pyrum Innovations AG: Chairman of the Supervisory Board increases his shareholding in the company 27.02.2023 / 19:00 CET/CEST The issuer is solely responsible for the content of this ... Seite 1
Michael Kapf Pascal Klein Ralf Schmidt Dillingen Saar Frankfurt Stock Exchange Oslo Stock Exchange

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Novel CRISPR Tool Activates Instead of Editing Human Immune Cell Genes

A research team used a method called CRISPRa to activate each gene in the genome in different cells, enabling them to test almost 20,000 genes in parallel. This allowed them to quickly learn the rules about which genes provide the most powerful levers to reprogram cell functions in ways that could eventually lead to more powerful immunotherapies.
Ralf Schmidt Zachary Steinhart Alex Marson Innovative Genomics Institute Institute Of Genomic Immunology Marson Lab

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