Page 10 - Randomized Controlled Trials News Today

In this mixed methods trial, Annabelle South and colleagues investigate different approaches to sharing the results of a clinical trial with its participants.

Research Article Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study Guillaume Butler-Laporte , Contributed equally to this work with: Guillaume Butler-Laporte, Tomoko Nakanishi Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing Affiliatio...

Research Article Integrated treatment of hepatitis C virus infection among people who inject drugs: A multicenter randomized controlled trial (INTRO-HCV) Lars T. Fadnes , Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing Roles Inve...

Ingrid Eshun-Wilson and co-workers assess the available evidence on community-based treatment initiation for people with HIV.

By Lars P. SyllCauses deduced in an experimental setting still have to show that they come with an export-warrant to the target population/system. The causal background assumptions made have to be justified, and without licenses to export, the value of ‘rigorous’ and ‘precise’ methods - and ‘on-average-knowledge’ - is despairingly small.

Can Dietary Fiber Reduce Toxins in Urine? Uremic toxins accumulate in the body during the course of CKD The study informs recommendations for using dietary fiber to reducing the uremic toxin among CKD patients in clinical practice Intake of high fiber foods such as whole breakfast cereals, berries, carrots, broccoli, peas, beans etc., is found to be helpful in decreasing uremic toxins in chronic kidney disease (CKD) condition. Can Dietary Fiber Reduce Toxins in Urine? The study published in the...

Author summary Why was this study done? Though cited in many countries’ national guidance, the evidence that individuals with pulmonary tuberculosis (TB) are rendered non-infectious by 2 weeks of effective TB treatment is challenged. This systematic review was commissioned by the World Health Organization to provide evidence to inform TB infection prevention and control guidelines. We sought to synthesise the available data on the clearance of potentially infectious TB bacteria from the ...

Lack of Vitamin D Does Not Raise the Risk of Type 1 Diabetes by Angela Mohan on  March 1, 2021 at 12:25 PM Vitamin D levels do not influence the chance of developing 1 diabetes in Europeans, according to a study published in the open-access journal PLOS Medicine by Despoina Manousaki from the CHU Sainte Justine and the University of Montreal, Canada and colleagues. Type 1 diabetes is a relatively common autoimmune disease that inflicts substantial lifelong illness and signif...

Research Article Comparative effect of physical exercise versus statins on improving arterial stiffness in patients with high cardiometabolic risk: A network meta-analysis Iván Cavero-Redondo, Affiliation Universidad de Castilla-La Mancha, Health and Social Research Center, Cuenca, Spain Affiliation Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom ⨯ Celia Alvarez-Bueno , Affiliation Institute of Applied Health Research, University o...

Ivermectin is effective for COVID-19: real-time meta analysis of 35 studies Posted on •100% of the 35 studies to date report positive effects. Early treatment is more successful, with an estimated reduction of 84% in the effect measured using a random effects meta-analysis, RR 0.16 [0.08-0.33]. Prophylactic use also shows high effectiveness. •100% of the 17 Randomized Controlled Trials (RCTs) report positive effects, with an estimated reduction of 71%, RR 0.29 [0.17-0.51]. •The probabil...