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Higher doses of heart failure guideline-directed medical therapy prescribed to patients with acute heart failure admission are associated with better outcomes

1. Higher doses of guideline-medical therapy (GDMT) within 2 weeks after discharge from an acute heart failure (AHF) admission were associated with a reduction in 180-day heart failure (HF) readmission, all-cause death, and quality of life (QOL) at 90 days. 2. Patients in high-intensity care (HIC) with higher GDMT doses at week 2 also had
Rating Level Rapid Optimization N Terminal Pro Brain Natriuretic Peptide Heart Failure Therapies Heart Failure

Ramping up heart failure medicines quickly reduces risk of readmission and death: STRONG-HF

There is a paucity of evidence for dose and pace of up-titration of guideline-directed medical therapies after admission to hospital for acute heart failure. Researchers have found in a new study...
United States France General Alexandre Mebazaa American Heart Association York Heart Association Meeting American Heart Association Scientific Sessions

High-intensity treatment strategy for heart failure reduces the risk of death or hospital readmission

Ramping up medication doses quickly after being hospitalized for acute heart failure resulted in a lower risk of dying or being readmitted for heart failure within the first six months after discharge, compared to usual care, according to a featured science research presentation today at the American Heart Association's Scientific Sessions 2022.
United States France General Alexandre Mebazaa Emily Henderson American Heart Association York Heart Association

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Safety, tolerability and efficacy of up-titration of guideline-directed medical therapies for acute heart failure (STRONG-HF): a multinational, open-label, randomised, trial

An intensive treatment strategy of rapid up-titration of guideline-directed medication and close follow-up after an acute heart failure admission was readily accepted by patients because it reduced symptoms, improved quality of life, and reduced the risk of 180-day all-cause death or heart failure readmission compared with usual care.
Coll Cardiol Van Spall Heart Failure Association European Society Of Cardiology Cardiology Society Of India Failure Long Term

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