Important targets for small cell lung cancer treatment: DLL3 & Notch
In this article, ACROBiosystems discusses the importance of DLL3 and Notch as therapeutic targets for small cell lung cancer treatment.
Source: news-medical.net
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Aberrant MAPK Signaling Offers Therapeutic Potential for Treatment of
Aberrant MAPK Signaling Offers Therapeutic Potential for Treatment of Ovarian Carcinoma
Source: dovepress.com
Mitochondrial functions of skeletal muscle in sarcopenia
Reviewing the effect of metabolites on mitochondrial functions in the pathogenesis of skeletal muscle aging. Read more
Endocrinol Lausanne J Clin Nutr Clin Pharmacokinet Alizadeh Pahlavani Biochim Biophys Acta Clin Epigenetics
Source: dovepress.com
m6A regulator and TME in non-small cell lung cancer
Investigation of the RNA N6-methyladenosine (m6A) modification in the progression of multiple tumours the tumour microenvironment in non-small cell lung cancer
South Korea Immunome Atlas Research Ethics Committee People Hospital Of Nanjing Medical University Cancer Genome Atlas Gene Expression Omnibus
Source: dovepress.com
UCHL1 promoted polarization of M1 macrophages
Identifying UCHL1 as a positive regulator of M1 macrophage polarization
Xingl Ubiquitination Deubiquitinase Mysm Kali Ma Laboratory Animals National Natural Science Foundation Of China Journal Of Inflammation Research
Source: dovepress.com
Dicer and bevacizumab inhibition hepatocellular carcinoma
In this study, we aimed to determine the relationship between Dicer and VEGF in HCC.
Source: dovepress.com
Regulatory mechanisms of lncRNAs in cancer glycolysis
163 are also involved in resistance to cisplatin, temozolomide and 5-fluorouracil via altering glycolysis in gastric cancer, glioblastoma and CRC, respectively. Interestingly, Fu et al reported that lncRNA plasmacytoma variant translocation 1 (PVT1) maintains Myc expression in Sjögren’s syndrome. This expression regulates proliferation and immune effects of CD4 + T cells by controlling glycolytic metabolism. 164 Investigating the role of the PVT1-T cell glycolysis axis in tumor models may pr...
Source: dovepress.com