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Predicting drug absorption in miniatured human liver

Kyoto University The Kazuo Takayama lab reports that PDMS-based liver-on-chip naturally absorb some drugs, which affects drug toxicity results. Liver-on-a-chip are miniaturized devices that capture the physiological and mechanical properties of the liver. They are commonly used by researchers to study how the liver metabolizes different compounds and drugs. In a new study seen in ACS Biomaterials Science & Engineering, CiRA Junior Associate Professor Kazuo Takayama and colleagues repo...
United States Emi Sano Fumiyoshi Yamashita Ryosuke Negoro Hiroyuki Mizuguchi Kazuo Takayama

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