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Study sheds new light on how obesity affects fat cells' mitochondria

The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors like diet and exercise play a role in the development and progression of obesity, scientists have come to understand that obesity is also associated with intrinsic metabolic abnormalities.
United States San Diego University Of California San Diego Hiroyuki Hakozaki Christopher Liddle Wenmin Xia

How obesity dismantles our mitochondria

<p>UC San Diego researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading to weight gain. They also found they could reverse the effect by targeting a single gene, suggesting a new treatment strategy for obesity.</p>
University Of California San Diego United States San Diego Yu Cao Yayun Xu Christopher Liddle Torrey Rhyne

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