Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19 nejm.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from nejm.org Daily Mail and Mail on Sunday newspapers.
Weight linked to risk of second cancer after breast cancer
Kaiser Permanente study has important public health implications given the number of breast cancer survivors with excess body weight.
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DENVER, April 5, 2021 /PRNewswire/ Breast cancer survivors who are overweight have a statistically significant increased risk of developing second primary cancers, according to results from a study conducted by Kaiser Permanente researchers and published in the Journal of the National Cancer Institute.
There are approximately 3.9 million breast cancer survivors in the United States today and studies have found women diagnosed with breast cancer have an 18% increased risk for developing a second cancer compared to the general population. This increased risk is likely due to shared risk factors between the first and second cancers, genetic susceptibility, and long-term effects of breast cancer treatment.
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Bottom Line: Among patients at high risk of melanoma, those who received routine skin cancer screening and education about skin self-exams were significantly more likely to be diagnosed with thinner and earlier stage melanomas.
Journal in Which the Study was Published:
Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research
Author: Michael Sargen, MD, a dermatologist and clinical fellow in the Division of Cancer Epidemiology and Genetics at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH)
Background: Whole-body screening for melanoma is currently routine for individuals at high risk for melanoma. These individuals include members of melanoma-prone families, categorized as having at least two relatives who have had melanoma, and those with inherited pathogenic gene variants that increase melanoma risk, said Sargen. However, the benefit of screening in melanoma-prone families has not be
Stem cell transplants offer long-term benefits for pediatric cancer patients receiving immunotherapy
Apr 1 2021
Children and young adults who receive CAR T-cell therapy for the most common childhood cancer - acute lymphoblastic leukemia - suffer remarkably fewer relapses and are far more likely to survive when the treatment is paired with a subsequent stem cell transplant, a new study finds.
Daniel Trey Lee is conducting pioneering clinical research in the battle against childhood cancer. Image Credit: UVA Health
The research, with an average follow up of nearly five years, suggests that stem cell transplants offer long-term benefits for young patients who receive the cutting-edge immunotherapy. CAR T-cell therapy results in complete remission in 60%-100% of patients initially, but the relapse rate is high. However, among those who received a stem cell transplant after CARs, the relapse rate was less than 10% two years later.