In a new study published in
Journal of Extracellular Vesicles, Chen-Yu Zhang s group at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig s group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in response to high levels of free fatty acids (FFAs). Theses β cell-derived exosomal miR-29s regulate glucose homeostasis through their manipulations on glucose output in liver.
Previously, Chen-Yu Zhang s group identified extracellular miRNA as a new form of cell-to-cell communication. They are among the first that reported the selective secretion of miRNAs under different physiological or pathological states; also, the uptake and function of secreted miRNAs in recipient cells. In the past decade, intensive studies have revealed the role of extracellular miRNAs in a range of biological processes. Thus, as a newly-emerged secretory factor, more insightful studies are needed to further reveal its relevance t
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IMAGE: A schematic illustration of the synthesis of GQDs with different stratagies and their applications in the domain of biosensors. view more
Credit: Authors
In a paper published in
NANO, researchers from Hubei, China discuss the top-down and bottom-up strategies for the synthesis of Graphene quantum dots (GQDs). The respective advantages and disadvantages of these methods are summarized. With regard to some important or novel ones, the mechanisms are proposed for reference. In addition, the application of GQDs in biosensors is highlighted in detail.
At present, various top-down methods, such as oxidative cutting, hydrothermal or solvothermal reactions, electrochemical oxidation, ultrasonic-assisted or microwave-assisted process, chemical vapor deposition (CVD) have been reported to produce GQDs. Meanwhile, the bottom-up methods have been developed rapidly, which mainly include carbonization methods and stepwise organic synthesis. Owing to excellent photo
Credit: Video credit belongs to the American Chemical Society.
Robots are widely used to build cars, paint airplanes and sew clothing in factories, but the assembly of microscopic components, such as those for biomedical applications, has not yet been automated. Lasers could be the solution. Now, researchers reporting in
ACS Applied Materials & Interfaces have used lasers to create miniature robots from bubbles that lift, drop and manipulate small pieces into interconnected structures. Watch a video of the bubble microrobots in action here.
As manufacturing has miniaturized, objects are now being constructed that are only a few hundred micrometers long, or about the thickness of a sheet of paper. But it is hard to position such small pieces by hand. In previous studies, scientists created microscopic bubbles using light or sound to assemble 2D items. Also, in a recent experiment, microbubbles produced by lasers, focused and powerful beams of light, could rotate shapes in 3D space
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Information Technology Daily
2021 JAN 15 (NewsRx) By a News Reporter-Staff News Editor at Information Technology Daily Researchers detail new data in Technology - Information Technology. According to news originating from Guiyang, People’s Republic of China, by NewsRx correspondents, research stated, “Smart grid is a fully automated power transmission network. It monitors and controls each user and grid node to ensure bidirectional flow of information and power between all nodes.”
Financial supporters for this research include National Natural Science Foundation of China (NSFC), Innovation Group Major Research Projects of Department of Education of Guizhou Province, Guizhou Provincial Science and Technology Foundation.