Food Dyes can Cause Colitis by Hannah Joy on May 14, 2021 at 4:57 PM
Two food colorants are the risk factors for causing inflammatory bowel disease (IBD)
Both genetic predisposition and environmental factors play a role in whether a person develops IBD or not
Artificial food colorants can cause colitis, which is an inflammatory bowel disease (IBD) when the immune system has become dysregulated, reveal Icahn School of Medicine researchers at Mount Sinai. The study, published in
Food Dyes can Cause Colitis
The study, conducted in mice, found that the mice developed colitis when they consumed food with the artificial food colorants FD&C Red 40 and Yellow 6 when a specific component of their immune system, known as cytokine IL-23, was dysregulated.
Food Dyes Cause Colitis When Immune System is Dysregulated, Mouse Study Finds
Source: Peter Bond / Unsplash
May 13, 2021
The results of research in mice by scientists at Icahn School of Medicine at Mount Sinai suggest that certain artificial food colorants can cause inflammatory bowel disease when the immune system has become dysregulated. The study found that mice with dysregulated expression of the immune system cytokine IL-23 developed colitis when they consumed food with the artificial food colorants Red 40 and Yellow 6. Development of colitis in the animals also required the presence of commensal bacteria that could metabolize the food dyes. The team claims the study, published in
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New York, NY (May 13, 2021) Artificial food colorants can cause disease when the immune system has become dysregulated, Icahn School of Medicine at Mount Sinai researchers report. The study, published in
Cell Metabolism in May, was the first to show this phenomenon.
The study, conducted in mice, found that the mice developed colitis when they consumed food with the artificial food colorants FD&C Red 40 and Yellow 6 when a specific component of their immune system, known as cytokine IL-23, was dysregulated. While it remains unclear whether food colorants have similar effects in humans, researchers plan to investigate exactly how cytokine IL-23 promotes the development of colitis after food colorant exposure.
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