5 Best Nootropics, Smart Drugs, and Brain Supplements of 2021 Chron 14 hrs ago Have you ever wanted to boost your brain power, be more productive and feel smarter? Join the crowd. The use of nootropics, also called “smart drugs,” and brain supplements is on the rise, with 14% of people already having tried them at least once. Nootropics come with a long list of claimed benefits, from improving short-term memory and battling brain fog to feeling more motivated and productive. However, choosing the best nootropics for your needs and lifestyle is no easy task. With so many nootropics to choose from, each one claiming to be the best, how do you really know which products are the most effective?