Being forced into isolation and confinement creates a number of potentially stressful demands. However, we might be able to learn a thing or two about coping with these demands, from people who choose a life in such settings. Despite the glorified image of being an astronaut, isolation and confinement remains a challenge for the star sailors that live above us. Demands associated with isolation and confinement are known as a red risk for long duration human spaceflight, which means they have the highest “likelihood of occurrence and the severity of their impact on human health, performance in mission, and long term quality of life”.