Best of both worlds? Should we mix or match vaccines? We’re sorry, this service is currently unavailable. Please try again later. Dismiss Best of both worlds? Should we mix or match vaccines? Can you try a Pfizer with an AstraZeneca? What about a Moderna with a Sputnik V? A quick guide to the science. Normal text size Why it matters Some studies have found mixing vaccine brands may give you as much (or even more) immunity to COVID. But Australian authorities and other experts are waiting on real-world data. Advertisement Cassandra Berry, a professor of immunology at Murdoch University, is waiting on her second dose of the AstraZeneca vaccine. But she expects an mRNA shot such as Pfizer (which requires only three weeks, not three months, between doses) would do just as well. “In fact, I think it’d be better,” she says.