URL copied Covaxin effective against multiple strain of coronavirus. India's indigenously developed Bharat Biotech's coronavirus vaccine â Covaxin â works against multiple variant of Covid19. According to the Indian Council of Medical Research (ICMR) study, COVAXIN neutralises against multiple variants of SARS-CoV-2 and effectively neutralises the double mutant strain as well. Covaxin has demonstrated overall interim clinical efficacy of 78 per cent and 100 per cent efficacy against severe COVID-19, the city-based company said on Wednesday announcing phase 3 interim analysis results of the vaccine. "The second interim analysis is based on accruing more than 87 symptomatic cases of COVID-19. Due to the recent surge in cases, 127 symptomatic cases were recorded, resulting in a point estimate of vaccine efficacy of 78 per cent (95%CI: 61-88) against mild, moderate, and severe COVID-19 disease," the vaccine maker said in a press release.