COVID-19 Antibodies, Vaccines Less Effective against Variant

Worrisome new coronavirus variants can evade antibodies that neutralize original virus, recent lab research shows
March 8, 2021
Physician assistant Philana Liang prepares a vial of COVID-19 vaccine on the Washington University Medical Campus. New research from Washington University School of Medicine in St. Louis has found that new variants of the virus that causes COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic, potentially undermining the effectiveness of vaccines and antibody-based drugs now being used to prevent or treat COVID-19.
Matt Miller/Washington University
New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic. With few exceptions, whether such antibodies were produced in response to vaccination or natural infection, or were purified antibodies intended for use as drugs, the researchers found more antibody is needed to neutralize the new variants.

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