E-Mail IMAGE: Pickhardt and colleagues' results showed that CRC prevention via screen detection of AN was highest with CTC, followed by mt- sDNA, and lowest with FIT due to the differing TPR... view more Credit: American Roentgen Ray Society (ARRS), American Journal of Roentgenology (AJR) Leesburg, VA, March 12, 2021--According to an open-access article in ARRS' American Journal of Roentgenology (AJR), compared with multi-target stool-DNA (mt-sDNA) and fecal immunochemical test (FIT), CT colonography (CTC) with 10 mm threshold most effectively targets advanced neoplasia (AN)--preserving detection while decreasing unnecessary colonoscopies. "CTC performed with a polyp size threshold for colonoscopy referral set at 10 mm represents the most effective and efficient non-invasive screening test for colorectal cancer (CRC) prevention and detection," clarified first author Perry J. Pickhardt from the department of radiology at the University of Wisconsin School of Medicine & Public Health.