Everything you need to know about secondary infertility Including the signs and causes of secondary infertility, possible tests and treatments, and what it can feel like. Photo: Cecilia Ruiz Vidya Ledsham was still hooked up to an IV in the hospital, recovering from the C-section delivery of her son, when she asked her doctor when she and her husband, Chris, could start planning for a second baby. “We wanted to have another right away because we wanted When Everett was a year old, they began trying to get pregnant again. “I thought we could just do the same things that had worked the first time,” she says. (Everett’s conception got a little nudge from a single dose of Clomid, a fertility medication that promotes ovulation.) But over the next five years, they did six cycles of fertility meds, then six cycles of IUI (intrauterine insemination, where a doctor inserts a thin tube through the cervix into the uterus to carry semen directly inside) and finally three cycles of IVF (in vitro fertilization, where the sperm and eggs are extracted, fertilized, and then an embryo is transferred into the uterus).