In Down syndrome cells, genome-wide disruptions mimic a senescence-like state : vimarsana.com

The disruption of gene transcription and cell function in Down syndrome is very similar to that seen in cellular aging, MIT scientists find. They used anti-senescence drugs to correct the errors in cell cultures, establishing senescence as a potentially targetable mechanism for future treatment.

Related Keywords

California , United States , Ashley Watson , Lindsey Guerin , Angelika Amon , Asaf Marco , Vishnu Dileep , Hiruy Meharena , Jacob Jaffe , Li Huei Tsai , Shruti Rengarajan , Malvina Papanastasiou , Elana Lockshin , Fatema Abdurrob , James Mullahoo , Alana Down Syndrome Center , Burroughs Wellcome Fund , Lumind Foundation , National Institutes Of Health , Alana Center , Picower Institute For , Alana Foundation , University Of California At San Diego , Cell Stem , Senior Alana Fellow , Picower Professor , Picower Institute , Grace Akatsu , National Institutes , Lana Down Syndrome Center , Own Syndrome , Hromosome 21 , Ene Transcription , Enescence , Ellular Aging , Risomy 21 , Iruy Meharena , Eural Progenitor Cells Npcs , I Huei Tsai , Neupoloidy , Nti Senolytic Drugs , Asatinib , Uercetin ,