Injecting mice with pulmonary endothelial cells can reverse

Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema


Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema
Researchers at Weill Cornell Medicine and NewYork-Presbyterian in New York have discovered that injecting mice with pulmonary endothelial cells-the cells that line the walls of blood vessels in the lung-can reverse the symptoms of emphysema. The study, which will be published July 21 in the
Journal of Experimental Medicine (
JEM), may lead to new treatments for chronic obstructive pulmonary disease (COPD), an inflammatory lung disease associated with smoking that is thought to be the third leading cause of death worldwide.
Emphysema is one of the characteristic features of COPD in which the tiny air sacs, or alveoli, within the lungs are gradually destroyed, leading to breathing difficulties and, eventually, respiratory failure. The loss of alveoli is accompanied by a remodeling of the lung's blood vessels that could indicate changes in the endothelial cells that form the blood vessel walls. Under normal circumstances, endothelial cells secrete molecules that help surrounding tissues maintain and repair themselves, but dysfunctional endothelial cells can drive various diseases, including tissue fibrosis and cancer.

Related Keywords

New York , United States , Shu Hisata , Arthurb Belfer , Emily Henderson , Weill Cornell , Shahin Rafii , Augustine Mk Choi , Angiocrine Bioscience , Alexandra Racanelli , Ansary Stem Cell Institute , Division Of Regenerative Medicine , Jichi Medical University , Weill Cornell Medicine , Experimental Medicine , Suzanne Weiss Dean , Co Senior Author , Regenerative Medicine , Genetic Medicine , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , வெயில் கார்னெல் , ஆகஸ்டின் ம்ஸீ சோய் , பதில் தண்டு செல் நிறுவனம் , பிரிவு ஆஃப் மீளுருவாக்கம் மருந்து , வெயில் கார்னெல் மருந்து , சோதனை மருந்து , ஸுஸ்யாந் வெயிஸ் டீன் , இணை மூத்தவர் நூலாசிரியர் , மீளுருவாக்கம் மருந்து , ஜெநெடிக் மருந்து ,

© 2025 Vimarsana