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Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema

Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema
Researchers at Weill Cornell Medicine and NewYork-Presbyterian in New York have discovered that injecting mice with pulmonary endothelial cells-the cells that line the walls of blood vessels in the lung-can reverse the symptoms of emphysema. The study, which will be published July 21 in the
Journal of Experimental Medicine (
JEM), may lead to new treatments for chronic obstructive pulmonary disease (COPD), an inflammatory lung disease associated with smoking that is thought to be the third leading cause of death worldwide.
Emphysema is one of the characteristic features of COPD in which the tiny air sacs, or alveoli, within the lungs are gradually destroyed, leading to breathing difficulties and, eventually, respiratory failure. The loss of alveoli is accompanied by a remodeling of the lung s blood vessels that could indicate changes in the endothelial cells that form the blood vesse ....

New York , United States , Shu Hisata , Arthurb Belfer , Emily Henderson , Weill Cornell , Shahin Rafii , Augustine Mk Choi , Angiocrine Bioscience , Alexandra Racanelli , Ansary Stem Cell Institute , Division Of Regenerative Medicine , Jichi Medical University , Weill Cornell Medicine , Experimental Medicine , Suzanne Weiss Dean , Co Senior Author , Regenerative Medicine , Genetic Medicine , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , வெயில் கார்னெல் , ஆகஸ்டின் ம்ஸீ சோய் , பதில் தண்டு செல் நிறுவனம் , பிரிவு ஆஃப் மீளுருவாக்கம் மருந்து ,

Researchers reverse emphysema in mice by injecting blood vessel wall cells

Researchers reverse emphysema in mice by injecting blood vessel wall cells
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

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Treatment with endothelial cells reverses emphysema in model

Treatment with endothelial cells reverses emphysema in model
cornell.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from cornell.edu Daily Mail and Mail on Sunday newspapers.

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Designer DNA Helps Treat Multiple Myeloma in Mice

Designer DNA Helps Treat Multiple Myeloma in Mice
by Angela Mohan on
January 21, 2021 at 12:20 PM
Targeted approach helps to treat myeloma by silencing IRF4, a gene that allows myeloma stem cells and tumor cells to proliferate and survive.
Past studies have shown that high IRF4 levels are associated with lower overall survival rates for patients with the disease, as per the team of researchers at University of California San Diego School of Medicine and Ionis Pharmaceuticals.
Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That s in part because cancer stem cells drive the disease cells that continually self-renew. If a therapy can t completely destroy these malignant stem cells, the cancer is likely to keep coming back. ....

San Diego , United States , University Of California San Diego , A Robert Macleod , Catriona Jamieson , Diseasesmultiple Myelomaepigeneticsoxidative , Lisa Ray , Translational Research Institute , National Cancer Institute , Drug Administration , Division Of Regenerative Medicine , Oncology At Ionis Pharmaceuticals , Sanford Stem Cell Clinical Center , Cancer Research , Uc San Diego Health , Ionis Pharmaceuticals , Moores Cancer Center , Uc San Diego School Of Medicine , California San Diego School , Cell Stem , Leslie Crews , Regenerative Medicine , Diego School , Altman Clinical , Koman Family Presidential Endowed Chair , Stem Cell Clinic ,

Designer DNA agent reduces myeloma stem cell abundance, lowers disease burden in mice

Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That's in part because cancer stem cells drive the disease cells that continually self-renew. If a therapy can't completely destroy these malignant stem cells, the cancer is likely to keep coming back. ....

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