Exercise of Warrants & Issue of Ordinary Shares and Total Voting Rights Exercise of Warrants & Issue of Ordinary Shares and Total Voting Rights DUBLIN, Ireland, and Boston MA, March 11, 2021, Amryt (Nasdaq: AMYT, AIM: AMYT), a global, commercial-stage biopharmaceutical company dedicated to acquiring, developing and commercializing novel treatments for rare diseases, announces that subscription rights relating to warrants to acquire 283,389 Ordinary Shares (the “Warrants”) have been exercised. In order to satisfy the exercise of the Warrants, the Company on 11 March 2021 issued 283,389 ordinary shares of £0.06 each (“Ordinary Shares”) from treasury. The Warrants were issued in connection with the listing of the Company on the AIM Market of the London Stock Exchange in 2016. Each warrant entitles the warrant holder to exercise subscription rights to subscribe for Ordinary Shares at a subscription price of £1.44 per Ordinary Share.