Justin Theroux Unveiled to Have Turned Down Offer to Star in 'Lost' TV Co-creator Damon Lindelof reveals the ex-husband of Jennifer Aniston was one of the people he had in mind to portray Jack Shephard, which eventually went to Matthew Fox, on the survival series. Apr 16, 2021 Lost", because he simply "wasn't interested." Co-creator Damon Lindelof reveals the "Mulholland Drive" star was one of the people he had in mind to portray spinal surgeon Jack Shephard on the survival series, but he politely turned down the opportunity - and the role eventually went to "Justin looking and sounding the way that he does, instantly the town [Hollywood bosses] decides, 'We're going to groom this guy to be the star of a Marvel movie,' " producer and screenwriter Lindelof told Esquire magazine as part of a Theroux cover story.