Advancing research on a common form of dementia Mayo Clinic researchers have assembled a team of international experts to investigate key proteins involved in Lewy body dementia. Lewy Body Dementia Center Without Walls Investigators from Mayo Clinic's Florida campus are leading a Lewy Body Dementia Center Without Walls research initiative funded by a National Institutes of Health (NIH) specialized center-cooperative agreement grant (U54). The overall goal of the Lewy body dementia multi-institutional Center Without Walls (CWOW) initiative is to deepen the understanding of how the Alzheimer's disease-related protein, amyloid-beta, and the Parkinson's disease-related protein, alpha-synuclein, interact to affect symptom presentation, disease progression and the underlying disease process in Lewy body dementia (LBD).