SCALA/Art Resource, New York The three are often venerated as saints and martyrs, and their supposed relics were transferred from Constantinople (modern Istanbul), possibly in the late 5th century, to Milan and thence to Cologne Cathedral in the 12th century. Devotion to the Magi was especially fervent in the Middle Ages, and they are some of the patron saints of travelers. Get a Britannica Premium subscription and gain access to exclusive content. Subscribe Now The Adoration of the Magi—i.e., their homage to the infant Jesus—early became one of the most popular themes in Christian art, the first extant painting on the subject being the fresco in the Priscilla Catacomb of Rome dating from the 2nd century. In the Middle Ages the Adoration of the Magi was often associated with two other major events of Jesus’ life: his baptism, during which the voice of God publicly declared Jesus to be his son, and the wedding at Cana, at which he revealed his divinity by changing water into wine. The three events, commonly celebrated on the same feast day, were frequently represented together in the monumental sculptures that decorated the churches of the period.