Oncofetal ecosystems linked to recurrence and immunotherapy

A team of clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS), Agency for Science, Technology and Research (A*STAR), the Harry Perkins Institute of Medical Research and global research partners, has found a causal link between the presence of oncofetal ecosystems (re-emergence of fetal programme/features driven by the tumor) in the primary liver cancer hepatocellular carcinoma (HCC) and cancer recurrence and response to immunotherapy.

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Singapore , Australia , Perth , Western Australia , Florent Ginhoux , Ankur Sharma , National Cancer Centre Singapore , Lab Head Of The Onco , Harry Perkins Institute Of Medical Research , Singapore Immunology Network , Research Council , Translational Research Investigator Award , Fetal Ecosystem Laboratory , Biomedical Research Council , National Research Foundation Singapore , Singapore National Research Foundation Senior Investigatorship , National Health , Research Future Fund , Agency For Science , Harry Perkins Institute , Medical Research , Nature Cancer , Slab Head , Onco Fetal Ecosystem Laboratory , Associate Professor Florent Ginhoux , Senior Principal Investigator , Immunology Network , Professor Pierce Chow , Senior Consultant Surgeon , Singapore General Hospital , Singapore Ministry , National Medical Research Council , Open Fund Large Collaborative Grant , Medical Research Council , Ideas Grant , Medical Research Future Fund , Mid Career Researchers , Cancer , Liver , Liver Cancer , Biomarker , Arcinoma , Fell , Healthcare , Hepatocellular Carcinoma , Mmunology , Immunotherapy , Ncology , Proton Therapy , Research , Technology ,