San Diego Convention Center to reopen with first major event this weekend and last updated 2021-07-30 18:07:48-04 SAN DIEGO (KGTV) â After more than a year, the San Diego Convention Center reopens its doors with the first event kicking off this weekend. San Diegoâs tourism took a big hit during the pandemic, but the city hopes to rebound with 30 events scheduled from August to December 2021. Organizers for San Diego Comic-Con, one of the cityâs biggest conventions, say they canât wait to be back inside of the venue. âWe are more than ready to join the list of the many conventions planned for this year as we prepare to launch Comic-Con Special Edition, November 26, 27, and 28,â says Comic-Con Spokesperson David Glanzer. âIt will be good to be back at our home away from home again.â