Study reveals how cells build 'mini-muscles' underneath thei

Study reveals how cells build 'mini-muscles' underneath their nucleus


Study reveals how cells build 'mini-muscles' underneath their nucleus
Research groups at the University of Helsinki uncovered how motor protein myosin, which is responsible for contraction of skeletal muscles, functions also in non-muscle cells to build contractile structures at the inner face of the cell membrane.
This is the first time when such 'mini-muscles', also known as stress fibers, have been seen to emerge spontaneously through myosin-driven reorganization of the pre-existing actin filament network in cells. Defects in the assembly of these 'mini-muscles' in cells lead to multiple disorders in humans, and in the most severe cases to cancer progression.

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Helsinki , Eteläuomen Läi , Finland , Jaakko Lehtimaki , Pekka Lappalainen , Emily Henderson , Hilife Institute Of Biotechnology , University Of Helsinki , Academy Professor Pekka Lappalainen , Docent Sari Tojkander , Veterinary Medicine , Factin , Cancer , Cell , Cell Membrane , Cortex , Microscopy , Muscle , Osteosarcoma , Protein , Research , Stress , Super Resolution Microscopy , ஹெல்சின்கி , பின்லாந்து , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் ஹெல்சின்கி , கால்நடை மருந்து , புற்றுநோய் , செல் , செல் சவ்வு , புறணி , நுண்ணோக்கி , தசை , ப்ரோடீந் , ஆராய்ச்சி , மன அழுத்தம் , அருமை தீர்மானம் நுண்ணோக்கி ,

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