Targeting Beta-amyloid in Its Dynamic State may Treat Alzheimers Disease by Karishma Abhishek on January 16, 2021 at 12:18 PM Nature Computational Science. formation of the toxic clusters which lead to the death of brain cells. Alzheimer's disease (AD) is a neurodegenerative disease that leads to gradual memory loss and behavioral changes. It is characterized by the formation of beta-amyloid plaques and the tau proteins in the brain tissues, long before the actual symptoms occur. ‘Beta-amyloid a pathological hallmark protein of Alzheimer's disease adopts a highly disordered shape in a matter of microseconds. This adds on to the need for a powerful tool to investigate these classes of proteins with fast and disordered motions for an effective treatment.’