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Targeting Beta-amyloid in Its Dynamic State may Treat Alzheimer's Disease


Targeting Beta-amyloid in Its Dynamic State may Treat Alzheimer’s Disease
by Karishma Abhishek on 
January 16, 2021 at 12:18 PM
Nature Computational Science.
formation of the toxic clusters which lead to the death of brain cells.
Alzheimer s disease (AD) is a
neurodegenerative disease that leads to gradual memory loss and behavioral changes. It is characterized by the formation of beta-amyloid plaques and the tau proteins in the brain tissues, long before the actual symptoms occur.
‘Beta-amyloid – a pathological hallmark protein of Alzheimer s disease adopts a highly disordered shape in a matter of microseconds. This adds on to the need for a powerful tool to investigate these classes of proteins with fast and disordered motions for an effective treatment.’ ....

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