Her in cardiac arrest . Im wolf blitzer. Youre in the situation room. Were follow two breaking news stories. Searchers are now racing to the site where a small plane crashed in waters off jamaica. It flew for hours unresponsive, past its florida destination, trailed by u. S. Fighter jets as it approached cuba. Well have full details on this story coming up. But first, a charter plane carrying American Military contractors has been ordered to land in iran on a flight out of afghanistan. Our correspondents and guests are all standing by for full coverage. Lets begin with Global Affairs correspondent elise labott at the state department. What do we know about this plane carrying u. S. Military contractors forced to land in iran . Wolf, this contract plane was flying from Bagram Air Base in afghanistan to dubai. It had about 100 americans and a couple dozen citizens from other coalition countries. The air control tower in iran contracted the pilots, told them their flight plan was out of date and told them to go back to afghanistan. The pilot said they did not have the enough fuel. Thats when the iranians ordered them to land or be intercepted. Mou now we understand that plane is still on the ground in iran. Officials telling us they hope it will be resolved shortly. Theyre waiting for clearance to take off, wolf. I want to clarify. The plan was forced to land in bandar abbas, not in ta ran. Thats right. We understand theyre still trying to work this out, get clarence to take off. We understand that plane still is on the ground at this moment, wolf. As far as you know, any direct communication with the americans on board . Not that we know of right now. Its being held between the u. S. And iranian officials. Trying to get that clearance but as soon as we understand whats going on, well let you know. Stand by. I want to bring inning pentagon correspondent Barbara Starr monitoring the story, as well. What are you hearing over there, barbara . These are somewhat routine, if you will, contract flights between afghanistan and dubai. They are not run by the u. S. Government. U. S. Planes do not fly through iranian air space. So this would have been a plane, our understanding it is a charter called fly dubai, a dubai aircraft. These charter flights bring contractors in and out of afghanistan all the time. The question is, of course, what the jobs may have been that the u. S. Personnel on board. Its our understanding that u. S. Troops, u. S. Contractors that hold very sensitive government contracts would not be on planes that fly through iranian air space. They do not board planes that fly through iran. This is most likely contractor who have other jobs. Everything perhaps from being a cook to working engineering and road construction. But to be clear, the United States government at this hour is not saying exactly who these 100 american are. As elise pointed out, the hope is to get in quietly resolved and get the plane on its way shortly. As far as you know, the discussions under way, i assume the United Arab Emirates that officials from the uae are involved. But are u. S. Officials, as far as you know, directly speaking with iranian officials . We asked the question. The answer we got is it we dont think so the at this time. They do not believe here at the pentagon that there is direct contact with the iranians on all of this. In fact, dubai, of course, has relationships very Close Relationships in some cases with iran, the likelihood is at this point theyre letting the government of dubai handle it, the dubai aviation authorities. It may be the quickest low key nonconfrontational way to get the situation resolved, wolf. How extraordinary, how unusual is this . Wolf, i have to tell you a few years back, i was on a charter flight out of afghanistan, and we took the same route, myself and our cnn crew and they announced that we had entered iranian air space. They announced when we had exited iranian air space shortly before crossing the gulf and landing in dubai. I think most americans who might be on a flight that the transits through iranian air space would breathe a little bit of a sigh of relief once theyre past iranian air space. It is a routine flight pattern in many cases. But again, for nonu. S. Aircraft. 100 americans 0 board . That is the estimate. I think several of us at cnn are getting that indication from u. S. Government officials. They believe there are about 100 american citizens on board and about 40 additional passengers from a number of other countries. But they are really at this point, theyre trying very hard, keep it low key. Get it resolved. Get that plane back up in the air and on its way to dubai. They want to, by all accounts, what the Obama Administration wants to do is get this resolved. Get that plane out of there. Get those americans out of iran and not face yet another crisis, wolf. Lets hope that happens. The plane takes off for dubai. Well stay in close touch with you barbara and elise labott over at the state department, as well. Theres another breaking story were following. An urgent search and rescue operation off the coast of jamaica. U. S. Coast guard aircraft are racing to the site where a small plane went down. Unresponsive it overshot its florida destination followed by u. S. Fighter jets as it flew toward cuba. Our aviation correspondent rene marsh joins with us the very latest. At this hour, wolf, this Search Mission off the coast of jamaica is happening. At 8 45 this morning, this turboprop aircraft carrying a businessman and his wife, we know their names, larry and jane glazer, we know that they took off from the rochester, new york, they were headed for naples, florida. The flight appeared normal until the plane was over north carolina. That is when the pilot radioed to air Traffic Controllers saying he had a problem. Lets take a listen to a portion of that audio. We need to descend down to 180. We have an indication thats not correct on the plane. Going to make things level. 250. We need to get lower. All right. Well, so you heard there the pilot again requesting to descend. After that request to descend, controllers lost contact with the plane. We know they scrambled two of f15 fighter jets to investigate. When the jets intercepted the plane, its occupants were slumped over and the windows were frosted indicating the plane had lost perhaps pra cabin pressure. Here is the scene one described. Take a listen to that. It was the first time we could see that he was actively breathing. Depending on how fast, he may regain consciousness once the aircraft starts descending for fuel. Okay. So there you heard there, very vivid description what the pilots saw. The fighter jets continued following the plane till it flew over cuba. It flew back over international waters, finally crashing 14 miles off the coast of jamaica. That is a whole 4 1 2 hours after the flight began. Question now, what happened on board . What happened in the cockpit . We know that norad officials believe it may be a case of hypoxia essentially a lack of oxygen causing the occupants to lose consciousness. Wolf. Were getting a statement in from the family of larry and jane glazer, the two people on board this plane. Larry glazer a wellknown developer in the rochester, new york, area. His kids issued the statement we are devastated by the sudden loss of our parents jane and larry. They loved and appreciated the opportunity to help build the community of rochester and we thank everyone in the community for their expressions of support. We understand there are many questions yet to be answered about todays events. We too are awaiting answers. At this time, we would appreciate the ability to mourn privately. Thank you for your understanding. Signed mindy glazer. And drew cuomo said i mourn the loss of larry and yan glazer. The glazers were innovative and generous people committed to vee vitalizing downtown rochester and making it a better place for all. I offer my deepest condolences to the glazer family and friends during this difficult and trying time. More now on the search operation thats under way. The u. S. Coast guard spokeswoman is joining us right now on the phone from key west. Where does this search operation stand as far as we know, marilyn . Right now, were working with the rescue Coordination Center in kingston, jamaica. We have an air crew that has arrived on scene along with two jamaican can aircraft crew. They were unable to locate a debris field. Were searching in the vicinity where we know that the plane dropped off radar, which is approximately 14 miles off the coast of port antonio, jamaica. Working in conjunction with jamaican officials, correct . Thats correct. The Defense Force out of the rescue Coordination Center in the kingston. Are they in charge of the investigation and youre supporting them . We are work ing incoordination. We are leading the investigation as far as the search and rescue is concerned and assisting the agencies in jamaica. What have they told you about what happened . Do you have any more information . We cant sfek late as far as what happened. I can tell you were in close coordination with the faa. It flew through cuban air space as your reporter mentioned before descending into the ocean. The flight departed from Greater Rochester International airport at about 8 26 about a filed flight plan of naples, florida, at 12 00 noon today. So how many pieces of equipment, planes an, ships, whatever youre doing are involved in the search operation . I dont think its a rescue operation. We could call it a search operation. Thats correct. We do have the c130 air crew that launched out of clear water, florida. We also have the coast guard cutter bernard c. Webber, 154foot cutter. One of our newest cutters. It has an estimated arrival of about semp hours. Have you seen any parts of this plane . No, we have not. But you have a good idea where it went into the water . We are searching in that vicinity 14 miles off the coast of port antonio. Thats the port were concentrating in right now. Youre familiar with this small private plane. Would it be most likely floating some place or would be submerged under the water . We cant speculate. But we are searching in the area. And you think something presumably in the coming hours will come up. Is that what youre saying . As we get information, this is a developing story for us. Were getting a lot of information. Were in very close coordination with the faa, with norad, with u. S. Norcon. Well make sure we make any Information Available to you an your viewers. Do you know how unusual, extraordinary this particular very sad incident is . Weve seen these incidents before and responded to plenty of search and rescue missions and Search Missions. The coast guard, one of its Core Missions is the rescue mission. I cant speculate as far as this case because its still a developing case. Spokeswoman for the u. S. Coast guard. Thanks very much. Well stay in close touch with you and update viewers as we get more information. Up next, president obama announces a coalitionings to destroy isis. U. S. Allies are getting on board. How will they carry out that mission . And the death of joan rivers. So what went wrong. Investigators are now looking into a medical procedure that left the comedienne in cardiac arrest. Where the reward was that what if tnew car smelledit card and the freedom of the open road . A card that gave you that im 16 and just got my first car feeling. Presenting the buypower card from capital one. Redeem earnings toward part or even all of a new chevrolet, buick, gmc or cadillac with no limits. So every time you use it, youre not just shopping for goods. Youre shopping for something great. Learn more at buypowercard. Com big day . Ah, the usual. Moved some new cars. Hauled a bunch of steel. Kept the supermarket shelves stocked. Made sure everyone got their latest gadgets. Whats up for the next shift . Ah, nothing much. Just keeping the lights on. laugh nice. Doing the big things that move an economy. See you tomorrow, mac. See you tomorrow, sam. Just another day at norfolk southern. Cozy or cool . Exactly the way you want it. Until boom, its bedtime your mattress is a battleground of thwarted desire. Enter the sleep number bed. Right now, all beds are on sale. Hes the softy. His sleep number setting is 35. Youre the rock, at 60. And snoring . Sleep numbers even got an adjustment for that. You can only find sleep number at a sleep number store. Head in for the final days of the biggest sale of the year. All beds on sale, with mattresses starting at 599. 99. Ends sunday. Know better sleep with sleep number. Lets get to our other top story. A dramatic announcement at the end of the urgent nato meeting. President obama says the United States is now leading a coalition of allies who are determined to degrade and destroy isis. Amid growing calls to expan the use of military force, the president says the dismantling of isis will be in his words systemic and methodical. Jim acosta is joining us from cardiff in wales with the latest. Jim . Wolf, president obama did not mince words today at this final day of the summit after taking so much heat after saying he didnt have a strategy for dealing with isis in syria and later saying he wanted to reduce the threat to a manageable problem. He delivered a much tougher message today. Heres what he had to say. You cant contain an organization that is running roughshod through that much territory causing that much havoc, displacing that many people. Killing that many innocents and enslaving that many women, the goal has to be to dismantle them. And also today, the Obama Administration announced it now has ten countries including the United States in what it considers to be an anti Isis Coalition. Those countries will be doing Different Things based on their varying capabilities. Secretary of state john kerry along with other Top Administration officials will be heading to the middle east in the coming days to start lining up arab participants for this coalition. Its a mission the president thinks will be successful. Heres what he had to say about that. I think it is absolutely critical that we have arab states and specifically sunni majority states that are rejecting the kind of extremist nilism were seeing out of sisal that say what is not what islam is about and are prepared to join us actively in the fight. And you know, my expectation is that we will see friends and allies and partners of ours in the region prepare to take action, as well as part of a coalition. Now, the president and secretary kerry both reiterated today there will be no u. S. Combat boots on the ground taking on isiss in iraq or syria. Secretary kerry in one nato session called it a red line for the administration. Thats probably not the term the white house would use because obviously, red lines have been crossed before. During this presidency, but it also underlines, wolf how far this administration wants to go in assuring americans even though they consider isis a serious threat and want to go after this terror group, theyre not putting combat forces on the ground to take them on. Jim acosta traveling with president in wales. As the United States forms this anti Isis Coalition with some of the nato allies seeks to bring in some of the arab nations, as well, could it also be teaming up with arch foal iran . Brian todd has been asked to take a closer look into this part of the story. We know that the u. S. And iran have a mutual hatred of isis. In their efforts to drives the group out of iraq, theres a lot of buzz out there somehow the two enemies could work together. They may have done that in one recent battle even if it wasnt planned. In the northern iraqi town of amerli, residents were under sieging from isis and feared a massacre. But in recent days, the siege was broken. Iraqs president acknowledges a combination of u. S. Air strikes and iranianbacked shiite militias on the ground drove isis away. Is there any cooperation or coordination between the u. S. And iran against isis . We do the not share intelligence with iran and have no plans to do so. An iranian official denies a report saying irans Supreme Leader ayatollah approved cooperation between his forces and the americans against isis. Specifically the report says hamannny sanctioned the general, the head of the qods force of the revolutionary guard to work with u. S. Forces. He may look like George Clooney but analysts say a better comparison would be don core leon. Hes a relatively mild mannered man but he has a done a very effective job at organizing the most brutal thugs that the Islamic Republic has. This photo posted by a group called diths of resistance is around the time of that siege. Cnn cannot independently verify that. Sulemanny would be among the strangest bedfellows america has had. As soon as you sit down with him, hes got the blood of americans on his hands. U. S. Officials believe assume mannys units provided a Lethal Weapon against american troops. It was his qods force which provided these very advanced explosive devices, its a misnomer to call them improvised explosive devices that penetrated armor on american vehicles and killed an awful lot of americans. Other reasons why a u. S. Iranian Alliance may not working . We want bashar an al assad out. We want a more inclusive government in baghdad. Iran would prefer a shia government. Theres also the matter of assume mannys dangerous reach beyond the middle east. U. S. Treasury Officials Say he was involved in a notorious plot on american soil overseeing officers who in 20 tried to assassinate iranians ambassador to the u. S. I remember when that story came out and the saudi ambassador to the United States ja bir was targeted by iranian terrorists. You say sulemanny was involved in that specific plot to try to kill the ambassador . It is thought the qods force oversaw that plot. Hes got his hands on everything the qods force does and was implicated in that plot. How much power does he have w