The Dow Jones Industrial average of the biggest stocks in the world, down 559 points, more than three percent. Some time lapse video to show you the first hour of the trading. Now were awe 3. 1 . Nasdaq down 200 points, the 500, the broader measure of the economy, off around 70 points or 3. 2 . Lon dos down more than 3 , japans nikkei dropped. The british pound is plummeting. The brexit referendum drew more than 30 million britons to the polls yesterday. More thanmore than 70 of voter. The measure passed with 52 of the vote. That will leave 27 members of the European Union, an alliance that began more than half a century ago to try to help prevent a third world war. David cameron announced he will be signing help led the cam fine stay or remain and took a huge political gamble when he called for the referendum three years ago. The Prime Minister says hell be out by october. I will do everything i can as Prime Minister to steady the ship over the coming weeks and months. But i do not think it would be right for me to try to be the captain that steers our country to it next destination this is not a decision i have taken lightly, but i do believe its in the to National Interest to have a period of stability and then the new leadership required. Stability in the future. One of the biggest supporters is the Uk Independence Party leader, he says Prime Minister cameroon did the honorable thing by stepping down and says june 23rd will go down in history as uks independence day. Its a victory for ordinary people. Decent people. A victory against the big merchant banks, against the big businesses and against big politics, and im proud of everybody to have the courage in the face of all the threats, everything day were told, had the gets to stand the guts to do the right thing. He says the vote shows the i is doom. And he says other members may follow britains lead. President obama spoke with Prime Minister cameron today. The president said, he called the british leader an outstanding friend and partner on the world stage. For ordinary people, decent people the ongoing changes and challenges raised by globalization, but while the uks relationship with the i eu will change, one thing that will not change is the relationship between our two nations. Donald trump happens to be in scotland for the reopening of one of his golf courses and says he supports brexit, even says president obama may have caused it by speaking out against the referendum during a visit to the United Kingdom in april. There is no real evidence of that. I was actually very surprised that president obama would come over and be so bold as to tell the people over here what to do. And i think that a lot of people dont like him. And a lot of people voted i think if he had not said it, think your result might have been different. What now for Great Britain. Can it remain united . Twothirds of voters in scotland voted to remain in the European Union. Scotlands leader today said it is highly likely the country will hold another referendum on leaving the United Kingdom. Brexit will be complicated and very time consuming. Once the process begins, which it hasnt, finalizing the divorce will take up to two years. What happens to the economies of the region and the world and to trade and immigration is completely unknown. Nothing like this has ever happened. We have extensive team fox coverage ahead, including what is next for the uk and the European Union. The latest reaction from lawmakers on capitol hill and how this could affect our economy in the United States. First, general benjamin hall. Reporter its been support shock over here. Overnight it feels they have just suddenly left and the country is reeling from the decision. It was late last night in the north of england, the first signs the government was really in trouble. It went downhill from there and did lead to David Camerons sudden resignation. There will be no initial change in the way our people can travel in the way our goods can move or the way our services can be sold. We must now prepare for a negotiation with the European Union. Reporter cameron said he would stay in power through october and the Party Conference but someone else has to take the hell and guide in the uk and that remain piston see who remains to be seen. What is the thinking who might replace Prime Minister cameron . Reporter has to be someone from the leave camp. There are two main options, michael, and boris johnson, the former mayor of london. He spoke directly to the people today. Today, i think all of us politicians should thank the british people because in a we they have been doing our job for us. They hire to us deal with the hard questions. And this year, we gave them one of the biggest and toughest questions of all. Reporter but the biggest is what lies ahead. Its dealing with this messy divorce from europe. Its renegotiating new trade deals and writing new laws in almost every sector. Not while trying to make sure the markets remain calm and europe doesnt fall apart. People looking to see how the uk survives, howl they do, and will they follow suit. We just dont know right now. Ben hall, our man in london. Let get context. What this means for the markets and our Retirement Funds and the big pure of the economy. John busse, the associate editor of wall street journal. Dont believe people saw this coming and i wonder if you have a sense what it means. How much more of this are we going to see . You heard the Independence Party leader say, this is antibig business, this is antiestablished politics. Words we have been hearing that same kind of rhetoric here in the u. S. President ial campaign from both the left and the right. Not just donald trump but bernie sanders. Youre hearing the same thing in political structures all over the world. In other countries in europe, particularly, the rise of rightwing antiimmigration parties in austria, poland, other places, increasingly in places like france. So this is a kind of period of alienation, of people feeling that politicians have not delivered for them. Theyre worriedded about their jobs, automation, globalization, has put those at risk. Theyre not seeing the benefits of existing political structure, and maybe fair or not, they are voicing their concern about it and youre seeing in britain the first real concrete impact globally. Largely, though not exclusively, largely this was about immigration. For so many people across Great Britain, and the ironic thing is that this doesnt solve any immigration issues they see at all. Not in the near term. This will take a long time. This is a vote to disentangle from the eu. There are regulations and laws that britain has signed on to, the way it conducts business in britain, is in concert with the way that other europeans do, as a result of this agreement over the last 50 years. So, now all that needs to be rewritten, not even the actual notice to the eu could take place for many, many months. Britain has to notify the eu that theres two years of negotiation on how town tangle that period in the middle where there are no rules for what happens for the next two years, three years . What cameron just said is correct. They operate as if they are part of the European Union until that is dissolved. That sounds awkward. Free Movement Across borders, beings relationship is the same. The immigration issue does not stop and its not just immigration for the middle east and europe. Its immigration of eastern europeans into the labor market in britain that has caused this kind of feeling of nationalism, to rise. And thats what youre seeing expressed here. Is this the beginning our stock markets, the dawes is down three percent, the send down four percent. The nasdaq down 0 four percent, is this a beginning, Quick Reaction and recovery . We dont know. And part of this we have to remember is that the market has had an incredible runup and can then over the last several weeks there was another runup of the market, and so a three Percent Movement is probably not that massive of an issue. The question is, the one youre asking, which is is this the beginning of an erosion . Theres going to be up certain any britain over the next two years. Does that lead to an economic slowdown in britain . Further economic slowdown in europe . Possible recession there, pitching the United States into either a further slowdown or recession, and the market erodes even further. That is the big concern and thats the big uncertainty right now. Bigger picture and as the markets close, john will be back with us later in the hour. Thank you. The former british Prime Minister said this is a mistake. So says tony blair today. The House Speaker of the United States, paul ryan, says despite what were seeing on wall street he is not wilder about the markets. Well take you to d. C. About that and have continuing coverage throughout the hour. 50 minuted until the final bell and a gloomy one on the corner of wall and broad. The Dow Jones Industrial average getting pummeled on the session with no end in sight. We have not reached 600points. Were at session lows at the moment and there is no sign of a late buyin. The downward movement continues. Real is touching a ray. Amazing is moving like one. Real is making new friends. Amazing is getting this close. Real is an animal rescue. Amazing is over twentyseven thousand of them. There is only one place where real and amazing live. Seaworld. Real. Amazing what are you doing . Sara, i love you, and. [phone rings] ah, its my brother. Keep going. Sara, will you marry. 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To avoid longterm injury, get medical help right away for an erection lasting more than four hours. If you have any sudden decrease or loss in hearing or vision, or any symptoms of an allergic reaction, stop taking cialis and get medical help right away. Ask your doctor about cialis and a 200 savings card grate britain throws a temper tantrum and invest yo racing for the exits. The dow down on session lows, 3. 4 on the day. The downward pressure continues. No signs of recovery this afternoon. Continuing coverage the historic brexit vote with folks in the United Kingdom choosing to leave the European Union, were already seeing the impact. Some pictures for how for you. They did not want this in belgium, the seat of the eu. Flowers spell out, please stay here. They did not. Inside European Union headquarters, officials who may be discussing where to get a stiff drink an the brits chose to leave that union. Markets around the globe have been nuts. This happens to be some students in south korea. A heck of a day to visit the Stock Exchange there. Big numbers on the board. This is japan. This guy handing out special editions of a newspaper announce thing brexit results. The stock market there had its worse day in five years. And finally, this is brussels where theyre working on the flags in front of the eu headquarters. One flag for each of the 28 members. One of those flags will be coming down. Lawmakers on capitol hill reacting to the decision to leave the eu. The House Speaker apology ryan saying the brexit vote will not affect the special relationship between the United States and the United Kingdom and the u. S. Markets will stabilize. President obama also said that relationship will not change. The president spoke out against brexit during a trip to the uk in april but today the white house said the can and the European Union will still be partners of the United States. Blake, the president just talked about brexit vote. Reporter he is out there in california earlier, the president just left there from a speech in california. Mentioned brexit. At the very beginning awe off the top he said he spoke with the british Prime Minister, David Cameron and the chancellor of germany, Angela Merkel. Calls cameron a good friend and a partner. As you maybed the president was in that region just a couple months ago and gave at the time what amounted to a warning to the voters there of the uk, saying that if they were to vote to leave the European Union, that they would go to the quote, as he put it, back of the queue related to trade deals and from that point on it could take some five to ten years to work out. Well, speaking earlier today in california, the president did not repeat that position. Listen here. Based on our conversation im confident that the uk is committed to an orderly transition out of the eu. We agreed that our economic and financial themes will teams will remain in close couldnt october as. Top Administration Officials from all over speaking out. Vicepresident joe biden was in ireland today. He said, quote, we have hoped for a different outcome but they fully respect the decision they have made, speaking of the uk voters. On the financial side. The treasury secretary, jack lew who had given warnings what a leave vote might mean, said today he is, quote, continuing to consult closely with leaders in the eu, the uk, and all around the globe. Politically what are republicans say. House Speaker Paul Ryan said the uk is an indispensable ally and tried to use this brexit vote to say that America Needs to lead. He reiterated that phrase a couple times during a News Conference today. One of the main issues to shake out here Going Forward is trade deals and the chairman of the house ways and means committee, kevin brady, said they should start getting a jump on that immediately. Brady writing in a statement, and im quoting in this time of uncertainty we should now begin to discuss a modern, new trade agreement with the uk that continues but expands the level of trade between our two nations. Trade deals. One of the Big Questions here Going Forward. No doubt. No clarity on what is ahead. Thank you. Isis supporters calling for new attacks in europe after the brexit vote. The intelligence and the analysis coming up as we continue to watch the Dow Jones Industrial average in the last 45 minutes of the trading day ends, downward pressure continues, off more than 3. 5 . The dow down 637 points and counting. Crowd sounds ] oooh [ brakes screech ] when your pain reliever stops working, your whole day stops. Excuse me, try this. But just one aleve can last 12 hours. Tylenol and advil can quit after 6. [ cheering ] so live your whole day, not part. With 12 hour aleve. She glows colorful mystery and adventure shes a guide shes a route a story and a song she is this day she is this moment she is this place and she belongs to you only in minnesota isis and al qaeda supporters are celebrating brexit on social media, calling for a tax in germany and belgium to, quote, paralyze europe. Our chief intelligence correspondent Catherine Herridge with a look at this from washington. Two groups that monitor terror groups on social media say the message went out from established isis and al qaeda accounts on telegram, an encrypted messaging service, urging followers to strike in europe and capitalize on the uncertainty after the vote. Exert say isis tries to capitalize of every major news event. Theres been a steady stream of isis chatter. The group sent out a kill list with 4,000 names and while we cant speak to authenticity of the list does appear to pull names and numbers from publicly available databases. This happened to be on business leader. The uks foreign office, the equivalent of our state depth, issued a warning that the threat level is high and eye says trained operatives want to hit british targets in response to this increased military pressure in iraq and syria. On top of this can were hearing from the cal quite magazine a call for followers to follow the example of the gunman in orlando. A special edition of the al qaeda online magazine called inspire and has he shooter Organization Mar mateen on the front cover. The most active and capable al qaeda affiliate and issued this new threebeige guide and were not here to promote details but it does follow a pattern where the group seeks to capitalize on lone wolf attac