Tweeps weigh in on explosive 'Oprah With Meghan and Harry' interview Share The âOprah with Meghan and Harry: A CBS Primetimeâ special was punted as one of the biggest interviews with members of the royal family and according to Twitter users, it delivered on the promises. Airing at 3am South African time on Monday, viewers from across the globe tuned in for the interview which started with Meghan Markle having a one-on-one session with talk show legend Oprah Winfrey. Meghan shared her experience of dating and marrying Prince Harry and some of the hardships she faced with the royal family and the British press.